A large red brick building with a clock tower and arched windows.

Spa Hotels & Resorts in Over-the-Rhine from AU$259

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Check availability on Over-the-Rhine Spa Hotels

Our top choices for Over-the-Rhine hotels with a spa

Treatment room

1. 21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati
4.5 star property
Downtown Cincinnati
8.6 out of 10, Excellent, (1,010 reviews)
  • cleanliness
    Luxuriate in rejuvenating spa treatments and facials at this boutique hotel with 3 dedicated wellness rooms.
The price is AU$259
includes taxes & fees
27 Sept - 28 Sept
21c Museum Hotel Cincinnati
Rooftop terrace

2. The Lytle Park Hotel, Autograph Collection

The Lytle Park Hotel, Autograph Collection
4.5 star property
Downtown Cincinnati
9.6 out of 10, Exceptional, (311 reviews)
The price is AU$520
includes taxes & fees
20 Sept - 21 Sept
The Lytle Park Hotel, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Over-the-Rhine

Pool
Breakfast included

Top Over-the-Rhine Hotel Reviews

21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

8/10 Good
"Great hotel! Very clean, comfy beds. Great location. Only reason I gave it 4 stars and it’s an individual preference but you have to request if you’d like a refrigerator in the room and same for ice and ice bin. Very minor just an inconvenience. Other than that it’s a wonderful hotel!"
Lea 2-night trip
Posted 1 hour ago
21c Museum Hotel Cincinnati

Frequently asked questions

Looking for a spa hotel in Over-the-Rhine?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Enjoy the live music scene and shops in Over-the-Rhine—your day trip starts here. Enjoy the art galleries and many popular restaurants during your holiday. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your stay.
What's there to see and do in Over-the-Rhine?
Experience Over-the-Rhine and visit Cincinnati Music Hall, Findlay Market and Hard Rock Casino Cincinnati. If you have a little extra time during your trip, you might want to make a stop at Rhinegeist Brewery and Ohio River Valley.
What is a Over-the-Rhine spa hotel?
Spa hotels in Over-the-Rhine provide lodging and have a full on-site spa offering services such as couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.

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