Top Hotels Near Odessa Regional Medical Center in Odessa from AU$76

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Accommodation near Odessa Regional Medical Center

Outdoor pool, open 10:00 AM to 10:00 PM, pool cabanas (surcharge)
Odessa Marriott Hotel & Conference Center

Odessa Marriott Hotel & Conference Center

4.0 star property
0.2 km from Odessa Regional Medical Center
9.2 out of 10, Wonderful, (459)
"Rooms and hotel were great"
United States
John
The price is AU$310
includes taxes & fees
20 Dec - 21 Dec
Odessa Marriott Hotel & Conference Center
Free breakfast
Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG

2.5 star property
3.1 km from Odessa Regional Medical Center
8.8 out of 10, Excellent, (465)
"Room was nicely cleaned & staff was very polite. "
United States
Mariano
The price is AU$163
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Odessa I-20 by IHG
Lobby
Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street

2.0 star property
1.9 km from Odessa Regional Medical Center
7.8 out of 10, Good, (497)
"Clean, quiet and a good price. The management here is quat"
United States
Ronald
The price is AU$82
includes taxes & fees
16 Dec - 17 Dec
Motel 6 Odessa, TX - 2nd Street
Desk, laptop workspace, blackout curtains, iron/ironing board
MainStay Suites Odessa I-20

MainStay Suites Odessa I-20

2.5 star property
3 km from Odessa Regional Medical Center
8.2 out of 10, Very good, (297)
"Very clean very spacious rooms friendly staff loved it"
United States
Jamayea
The price is AU$130
includes taxes & fees
19 Dec - 20 Dec
MainStay Suites Odessa I-20
Suite, 1 King Bed, Jetted Tub, Pool View (with Sofabed) | View from room
SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa

3.0 star property
2.7 km from Odessa Regional Medical Center
7.4 out of 10, Good, (75)
"I like it here"
United States
Jesus
The price is AU$145
includes taxes & fees
7 Dec - 8 Dec
SureStay Plus Hotel by Best Western Odessa
Living area
DELUX INN

DELUX INN

2.5 star property
2.5 km from Odessa Regional Medical Center
6.8 out of 10, (23)
"Best hotel "
United States
Poncho
The price is AU$113
includes taxes & fees
16 Dec - 17 Dec
DELUX INN
Blackout curtains, free WiFi, bed sheets
Motel 6 Odessa, TX

Motel 6 Odessa, TX

2.0 star property
2.8 km from Odessa Regional Medical Center
6.8 out of 10, (550)
"The room was very clean. And management was very helpful."
United States
Bonnie
The price is AU$111
includes taxes & fees
3 Jan - 4 Jan 2026
Motel 6 Odessa, TX
Children’s area
Staybridge Suites Odessa - Interstate HWY 20 by IHG

Staybridge Suites Odessa - Interstate HWY 20 by IHG

3.0 star property
4.6 km from Odessa Regional Medical Center
8.8 out of 10, Excellent, (135)
"Great staff! "
United States
Andrew
The price is AU$144
includes taxes & fees
21 Dec - 22 Dec
Staybridge Suites Odessa - Interstate HWY 20 by IHG
Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool loungers
Hawthorn Extended Stay by Wyndham Odessa

Hawthorn Extended Stay by Wyndham Odessa

3.5 star property
4.7 km from Odessa Regional Medical Center
8.6 out of 10, Excellent, (265)
"Clean room, reasonable price and restaurant on site which was perfect after a long day of driving"
United States
Kimberly
The price is AU$170
includes taxes & fees
12 Dec - 13 Dec
Hawthorn Extended Stay by Wyndham Odessa
Property amenity
Candlewood Suites Odessa by IHG

Candlewood Suites Odessa by IHG

2.5 star property
4.6 km from Odessa Regional Medical Center
8.6 out of 10, Excellent, (190)
"It was a smaller place than i have stayed before, it does not have a pool, but still great place to stay."
United States
Alice
The price is AU$152
includes taxes & fees
19 Dec - 20 Dec
Candlewood Suites Odessa by IHG
Lobby
TownePlace Suites by Marriott Odessa

TownePlace Suites by Marriott Odessa

3.0 star property
5.4 km from Odessa Regional Medical Center
9.0 out of 10, Wonderful, (511)
"Great service and breakfast was very good."
United States
Iris
The price is AU$167
includes taxes & fees
23 Dec - 24 Dec
TownePlace Suites by Marriott Odessa
Exterior
Fairfield Inn & Suites Odessa

Fairfield Inn & Suites Odessa

2.5 star property
5.3 km from Odessa Regional Medical Center
8.8 out of 10, Excellent, (411)
"We had a great stay! The staff was very friendly and helpful, especially Nizhoni at the front desk-she was amazing. The facility and rooms were clean, the beds were comfortable, and the complimentary breakfast had plenty of options. Would definitely stay here again. "
United States
Karinna
The price is AU$149
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites Odessa
Full-sized fridge, microwave
Parkway Inn

Parkway Inn

2.0 star property
5 km from Odessa Regional Medical Center
8.6 out of 10, Excellent, (24)
"Nice and remodeled rooms "
United States
Eleuterio
The price is AU$122
includes taxes & fees
7 Dec - 8 Dec
Parkway Inn
View from room
MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa

3.5 star property
6 km from Odessa Regional Medical Center
9.0 out of 10, Wonderful, (1000)
"Clean rooms, staff was very nice"
United States
Karen
The price is AU$173
includes taxes & fees
19 Dec - 20 Dec
MCM Elegante Hotel and Conference Center Odessa
Desk, laptop workspace, blackout curtains, iron/ironing board
Sleep Inn & Suites Odessa near University

Sleep Inn & Suites Odessa near University

2.5 star property
5.2 km from Odessa Regional Medical Center
8.6 out of 10, Excellent, (464)
"Great staff"
United States
Stephanie
The price is AU$111
includes taxes & fees
2 Jan - 3 Jan 2026
Sleep Inn & Suites Odessa near University
Outdoor pool
Hampton Inn by Hilton Odessa

Hampton Inn by Hilton Odessa

2.5 star property
5.3 km from Odessa Regional Medical Center
8.6 out of 10, Excellent, (363)
"Always a great place to stay!!!"
United States
Xavier
The price is AU$153
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn by Hilton Odessa
Property entrance
Executive Inn Odessa

Executive Inn Odessa

2.5 star property
3.2 km from Odessa Regional Medical Center
7.4 out of 10, Good, (189)
"Excelente "
Mexico
Angely
The price is AU$76
includes taxes & fees
8 Dec - 9 Dec
Executive Inn Odessa
Full-sized fridge, microwave, stovetop, coffee/tea maker
Studio 6 Odessa, TX

Studio 6 Odessa, TX

2.5 star property
4.6 km from Odessa Regional Medical Center
8.0 out of 10, Very good, (240)
"The staff was very welcoming and accommodating. I was able to check in early and my room was clean, sanitized, and ready. Not the most modern motel but definitely worth the value."
United States
Mark
The price is AU$121
includes taxes & fees
12 Dec - 13 Dec
Studio 6 Odessa, TX
Front of property – evening/night
Holiday Inn Odessa by IHG

Holiday Inn Odessa by IHG

3.0 star property
6.4 km from Odessa Regional Medical Center
8.8 out of 10, Excellent, (454)
"Great staff, clean room, convenient location."
United States
Enedina
The price is AU$145
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Odessa by IHG
Lobby
Comfort Inn & Suites, Odessa I-20

Comfort Inn & Suites, Odessa I-20

2.5 star property
4.6 km from Odessa Regional Medical Center
7.8 out of 10, Good, (565)
"Good place to stay"
United States
Bobby
The price is AU$124
includes taxes & fees
3 Jan - 4 Jan 2026
Comfort Inn & Suites, Odessa I-20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Odessa Regional Medical Center Hotel Reviews

MCM Grande Hotel FunDome Odessa

MCM Grande Hotel FunDome Odessa

10/10 Excellent
"Great! Will Stay Again."
Alexander 1-night trip
Posted 3 days ago
MCM Grande Hotel FunDome Odessa

Hotels near other Odessa Regional Medical Center attractions

Odessa Jackrabbit Statue

You can learn about the history of Odessa when you stop by Odessa Jackrabbit Statue. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

White-Pool House

4.3/5 (20 reviews)
You can find out about the history of Odessa when you stop by White-Pool House. Experience the area's entertainment venues or attend a sporting event.
See properties

Frequently asked questions

What's the area like around Odessa Regional Medical Center?
Odessa Regional Medical Center is located in Odessa. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 15 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Odessa Regional Medical Center?
Adjacent to Odessa Regional Medical Center, Odessa Marriott Hotel & Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a few miles include MCM Grande Hotel FunDome Odessa and Motel 6 Odessa, TX - 2nd Street.
How many hotels can I expect to find near Odessa Regional Medical Center?
Expedia has 15 hotels and other accommodation options within a mile from Odessa Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Odessa Regional Medical Center, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best deals near Odessa Regional Medical Center.
What can I see and do near Odessa Regional Medical Center?
Study the collections at White-Pool House, Ellen Noel Art Museum or Parker House Museum. Create some family memories at Altitude Trampoline Park and Fun City. Attractions like Globe of the Great Southwest and Presidential Museum and Leadership Library highlight the local culture.