A calm river with clear water, surrounded by dense trees and rocky banks.

Search O Brien hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for O Brien hotels

1. Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,080 reviews)
"Nice room and great breakfast."
United States
James
The price is AU$133
includes taxes & fees
18 Aug - 19 Aug
Best Western Plus Lake City

2. Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (136 reviews)
"wonderful, quiet, a hide a way for a fun stay"
United States
Diane
The price is AU$135
includes taxes & fees
5 Aug - 6 Aug
Cindys Motel

3. Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,007 reviews)
"Nice place to stay"
United States
KHAJA
The price is AU$157
includes taxes & fees
18 Aug - 19 Aug
Comfort Suites Lake City

4. Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (742 reviews)
"Comfortable beds, quiet, nice staff."
United States
Mari
The price is AU$105
includes taxes & fees
9 Aug - 10 Aug
Super 8 by Wyndham Lake City

5. Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,001 reviews)
"Room was clean and breakfast was great!!!"
United States
Justo
The price is AU$167
includes taxes & fees
16 Aug - 17 Aug
Hampton Inn & Suites Lake City

6. Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (862 reviews)
"The rate per night was reasonable, the breakfast was amazing, and unlimited free coffee was prefect, and the staff was very helpful and accommodating when we had an issue after the rain."
United States
Trisha
The price is AU$165
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Express & Suites Live Oak by IHG

7. Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,006 reviews)
"Stayed here on more than one occasions. Would stay there again."
United States
Michael
The price is AU$161
includes taxes & fees
9 Aug - 10 Aug
Tru by Hilton Lake City

8. La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
3.0 star property
Lake City
8.8 out of 10, Excellent, (1,136 reviews)
"Great stay"
United States
Priscilla J
The price is AU$147
includes taxes & fees
5 Aug - 6 Aug
La Quinta Inn & Suite by Wyndham Lake City

9. Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
White Springs
7.2 out of 10, Good, (689 reviews)
"Cheap and food enough"
United States
william
The price is AU$80
includes taxes & fees
30 Aug - 31 Aug
Quality Inn White Springs Suwanee

10. Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (259 reviews)
"Cleaned place, good staff, basic breakfast"
United States
Adoniram
The price is AU$172
includes taxes & fees
12 Aug - 13 Aug
Fairfield Inn & Suites Lake City

11. Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,004 reviews)
"It was great for overnight stop for our road trip. We slept well, no noise from the road and good beds."
United States
Larissa
The price is AU$104
includes taxes & fees
5 Aug - 6 Aug
Americas Best Value Inn Lake City

12. Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (33 reviews)
"This is a lovely place to visit"
United States
Beth
The price is AU$172
includes taxes & fees
15 Aug - 16 Aug
Suwannee River Rendezvous

13. Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,003 reviews)
"Breakfast was nice, friendly staff, convenient location. Clean room"
United States
Renee
The price is AU$162
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn & Suites Lake City by IHG

14. Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very good, (1,004 reviews)
"Great breakfast; clean rooms; very friendly staff."
United States
Lucille
The price is AU$123
includes taxes & fees
11 Aug - 12 Aug
Quality Inn Lake City

15. Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (806 reviews)
"Great place to stay we will be back soon. "
United States
William
The price is AU$196
includes taxes & fees
9 Aug - 10 Aug
Home2 Suites by Hilton Lake City

16. Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (280 reviews)
"Loved our stay"
United States
Tonya
The price is AU$186
includes taxes & fees
11 Aug - 12 Aug
Courtyard By Marriott Lake City

17. Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,000 reviews)
"Great for a short stay and clean"
United States
Brizheet
The price is AU$101
includes taxes & fees
5 Aug - 6 Aug
Days Inn by Wyndham Lake City I-75

18. Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.6 out of 10, Good, (636 reviews)
"For the price - all was great!"
United States
Teresa
The price is AU$104
includes taxes & fees
5 Aug - 6 Aug
Palms Garden Inn

19. Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
7.6 out of 10, Good, (219 reviews)
"Amazing stay"
United States
Pennee
The price is AU$104
includes taxes & fees
5 Aug - 6 Aug
Motel 6 – Lake City, Fl – Medical Center

20. Regal Inn

Regal Inn
2.5 star property
Lake City
8.4 out of 10, Very good, (614 reviews)
"First I was not sure if we wanted to stay there, but our room was pretty nice, price was excellent every thing was very clean. Lady at the front desk was very nice."
United States
Samuel
The price is AU$99
includes taxes & fees
5 Aug - 6 Aug
Regal Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

Recent Reviews in O Brien

More cheap accommodation in O Brien

Find out more about O Brien

Top reasons to visit O Brien

  • Stunning Natural Scenery: O'Brien boasts breathtaking landscapes perfect for outdoor activities like hiking and nature walks.
  • Outdoor Adventures: Enjoy thrilling experiences such as jet skiing and leisurely river walks in a picturesque setting.
  • Family-Friendly Atmosphere: The charming neighbourhoods cater to families, making it ideal for a memorable holiday.
  • Diverse Accommodation Options: From pet-friendly motels to historic hotels, there's something for every traveller's needs.
  • Cultural Experiences Nearby: A short drive to downtown San Antonio offers vibrant dining and cultural attractions.

Find great hotels near O Brien

Discover the charm of O'Brien, Florida, where a variety of accommodation options await you. From inviting motels to historic hotels, this quaint location caters to all travellers. Whether you seek pet-friendly lodgings, a welcoming atmosphere for LGBTQIA guests, or convenient amenities for business travel, O'Brien has it all. Explore the picturesque O'Brien Riverwalk Boutique Hotel and other delightful stays that promise a memorable holiday experience.

  • Americas Best Value Inn Lake City: Located 29km from O Brien, Americas Best Value Inn Lake City is a charming motel with a guest rating of 8.6. This property is an excellent choice for travellers seeking a pet-friendly environment, offering amenities such as a fee-waived service for service animals and specific pet policies allowing certain pets on-site. Guests appreciate the welcoming atmosphere and comfortable accommodations, making it an ideal place to unwind after a day of exploration.
  • Baymont by Wyndham Lake City I-75: Situated 29km from O Brien, Baymont by Wyndham Lake City I-75 is a versatile hotel designed to cater to families, business travellers, and pet owners alike. The hotel provides essential amenities for children, including complimentary cribs, ensuring a convenient stay for families. With a pet-friendly policy that includes restrictions and fees, this property balances comfort and practicality, making it an inviting option for various types of visitors.
  • Comfort Suites Lake City: Comfort Suites Lake City, located 29km from O Brien, boasts an impressive guest rating of 9.4. This hotel is tailored for business travellers, offering a range of facilities designed to support work needs while ensuring a comfortable stay. The well-appointed rooms and attentive service create a professional yet relaxed atmosphere, making it a preferred choice for those visiting the area for business purposes.

Where to stay near O Brien

For those seeking outdoor adventures and breathtaking scenery, O'Brien, Florida, presents an idyllic getaway. Experience the charm of family-friendly neighbourhoods while enjoying luxurious accommodations with friendly staff at affordable rates. Explore the nearby picturesque landscapes, perfect for hiking and nature walks. Just a short drive away, discover the vibrant atmosphere of downtown San Antonio, where cultural experiences and delightful dining await. Embrace the warm hospitality of the region and create unforgettable memories in this beautiful part of Florida.

  • Branford: Located a mere 10km from O'Brien, Branford boasts a vibrant outdoor scene that attracts adventurers and nature enthusiasts alike. The town is known for its stunning scenery and plethora of recreational areas. Visitors can indulge in thrilling activities such as underwater sports or explore the nearby national state park. Branford’s natural landmarks, including a picturesque river and various water features, provide the perfect backdrop for a day of exploration and relaxation.
  • Mcalpin: Situated 11km away from O'Brien, Mcalpin is another gem in the region that offers a moderately seasonal influx of visitors. This city is a haven for those seeking outdoor experiences and scenic beauty. With access to recreational areas and adventure activities, guests can immerse themselves in the tranquil surroundings. The local attractions such as the river and national state park make Mcalpin an ideal destination for nature lovers and thrill-seekers alike.
  • Alton: A charming village located 19km from O'Brien, Alton captivates visitors with its serene landscapes and inviting atmosphere. Although its visitor numbers are relatively stable throughout the year, the peaks occur in March and October to November. Alton’s scenic river offers a peaceful retreat for those looking to unwind and enjoy the natural beauty of Florida. It’s a perfect spot for leisurely strolls and quiet reflection amidst the picturesque surroundings.

Things to do near O Brien

O'Brien, Florida, offers a delightful escape for outdoor enthusiasts, featuring stunning scenery and a range of adventurous activities. Visitors can enjoy jet skiing, leisurely river walks, and even a trip to the local bowling alley for some fun. With its recreational areas, O'Brien is perfect for those seeking adventure and relaxation in a beautiful natural setting.

Shopping

The nearest shopping option in O'Brien is the local market, where you can find handmade crafts and local produce. If you're up for a drive, head to Lake City Mall, about 32km away, featuring a range of popular retail stores and eateries for a more extensive shopping experience.

Recreation

In O'Brien, Florida, the Suwannee River State Park offers serene nature trails and picnic spots for relaxation. Nearby, the Healing Waters Spa provides rejuvenating treatments, allowing you to unwind amidst tranquil surroundings and enjoy a variety of holistic therapies tailored to refresh your mind and body.

Adventure

Experience the thrill of motor racing at North Florida Speedway, located 32km from O Brien. Feel the adrenaline as you watch high-speed races, enjoy the vibrant atmosphere, and immerse yourself in the excitement of this dynamic racing venue.

Nightlife

Experience the laid-back vibe at the O'Brien Cafe, where you can enjoy live music and a selection of local wines. For a lively atmosphere, visit the nearby O'Brien Sports Bar, serving up tasty pub grub and a variety of beers in a friendly setting.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for O Brien

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in O Brien are January, August and November, where the prices are slightly lower. This is in comparison to March, May and October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in O Brien is Monday. The most expensive day to stay in O Brien is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia's search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. To discover the most affordable prices and offers, arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can potentially save money by combining your O'Brien hotel reservation with your flights and activities through an Expedia package deal.

Find the best attractions near O Brien

O'Brien, Florida, is ideal for those seeking outdoor adventures and stunning scenery. Visitors can explore national and state parks, as well as picturesque rivers and lakes, making it a perfect destination for families and nature enthusiasts alike. With a variety of attractions that cater to outdoor experiences, O'Brien promises a memorable holiday filled with exploration and enjoyment of the natural beauty surrounding the area.

  • Suwannee River: A picturesque river located 10km from O Brien, the Suwannee River offers stunning outdoor scenery, perfect for leisurely canoeing or kayaking. Enjoy the tranquillity as you take in the lush surroundings and the vibrant wildlife that calls this area home.
  • Ichetucknee Springs State Park: Situated 18km away, this national park is a haven for adventure lovers. With its crystal-clear springs, visitors can indulge in tubing, snorkelling, or hiking along scenic trails, all while being enveloped in breathtaking natural beauty.
  • Branford Public Library: Just 8km from O Brien, this charming library provides a welcoming atmosphere for families. Explore a rich array of cultural resources and community events that foster learning and connection among visitors of all ages.

Best time to go to O Brien

The best time to visit O Brien is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly Low
February57.9°F (14.4°C)Light RainMostly SunnyAverageAverage
March62.8°F (17.1°C)Light RainMostly SunnyAverageSlightly High
April69.1°F (20.6°C)Light RainMostly SunnyAverageAverage
May75.4°F (24.1°C)Light RainMostly SunnyModerately LowSlightly High
June80.2°F (26.8°C)Light RainMostly SunnyModerately HighAverage
July81.5°F (27.5°C)Light RainMostly SunnyModerately HighAverage
August81.3°F (27.4°C)Light RainMostly SunnyModerately HighSlightly Low
September77.9°F (25.5°C)Light RainMostly SunnyAverageAverage
October70.9°F (21.6°C)No RainMostly SunnyAverageSlightly High
November61.7°F (16.5°C)Light RainMostly SunnyModerately LowSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnyAverageAverage

The nearest major airports for your trip to O Brien

Accessing O'Brien, Florida is convenient through several nearby airports. Jacksonville International Airport (JAX) is situated 130km away, with nearby hotels such as the DoubleTree by Hilton Hotel Jacksonville Airport, located 483m from the airport, and the Hyatt Regency Jacksonville, 19km away. Tallahassee International Airport (TLH) is 140km from O'Brien, with quality accommodation options like the DoubleTree by Hilton Hotel Tallahassee and Hotel Duval, both 8km from the airport. Lastly, Gainesville Regional Airport (GNV) is just 76km away, featuring hotels like the DoubleTree by Hilton Gainesville and Hotel Indigo Gainesville-Celebration Pointe, both 13km from the airport.

Frequently asked questions

What is the best area to stay in O Brien?
The best area to stay in O'Brien, Florida, is along the Suwannee River, particularly around the public boat ramps and access points.

This area is the main draw for visitors to O'Brien, as it provides direct access to the natural beauty and recreational opportunities of the Suwannee River. You'll find a scattering of accommodations, from holiday rentals to small, independent motels, often with direct riverfront access or just a short drive away. This allows for convenient enjoyment of activities like fishing, kayaking, and boating.

Families will find this area particularly appealing due to the easy access to water-based activities. Many properties offer amenities like barbecue areas and space for children to play, making it simple to enjoy the outdoors together. The nearby Spirit of the Suwannee Music Park also hosts various events throughout the year, which can be a fun addition to a family holiday.

For couples looking for a relaxed escape, staying by the river offers a peaceful setting. You can enjoy quiet evenings by the water, explore the river's springs, or simply unwind away from city life.
When is the best time to go to O Brien?
The best time to visit O'Brien, Florida, is typically during the spring (March to May) and autumn (September to November) months.

During these periods, the weather is generally mild and pleasant, with comfortable temperatures, making it ideal for enjoying outdoor activities like swimming, fishing, and exploring the natural springs without the intense heat and humidity of summer or the cooler temperatures of winter. The spring also brings blooming wildflowers, adding to the area's natural beauty.

For couples looking for a relaxing escape, these shoulder seasons offer a good balance of agreeable weather and fewer crowds compared to peak summer. You'll find it easier to enjoy the tranquility of the Ichetucknee Springs State Park or the Suwannee River without feeling overwhelmed by other visitors.

Families travelling with children might also find these times more comfortable for outdoor adventures.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in O Brien.
How can I save on a hotel booking in O Brien with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on O Brien hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in O Brien?
Prices for hotels in O Brien often vary, but you can find a great deal from AU$80 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.