Nuevo Santiago Holidays

Book a Hotel + Flight or Car together to unlock savings

Plan, book, travel with confidence
Better together
Save up to AU$703 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Nuevo Santiago Holiday

Our pick of the best Nuevo Santiago Hotel Deals

Hotel Mykonos Panama

Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas

Fully refundableReserve now, pay when you stay

AU$144

11 Nov - 12 Nov

includes taxes & fees

8.8/10 Excellent! (533 reviews)

Great room, great food and great price

Reviewed on 29 Oct 2025

Hotel Galería

Vía Interamericana Santiago, Km 232.88, Nuevo Santiago

Fully refundableReserve now, pay when you stay

AU$108

11 Nov - 12 Nov

includes taxes & fees

8.2/10 Very Good! (199 reviews)

Perfect overnight stop

We stayed over night on our way home from Panama City. I used the pool, very clean and refreshing. Everything was clean and comfortable. I couldn’t get hot water in the shower, but my son had no problem. The breakfast was excellent.

Reviewed on 21 June 2025

Hotel Plaza

Interamericana, Nuevo Santiago, Veraguas

It's a 35 $ a night hotel !!

Reviewed on 21 Aug 2023

Get rates

See all 12 properties in Nuevo Santiago

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.