A large eye sculpture in a park surrounded by trees.

Spa Hotels & Resorts in Northeast Missouri from AU$133

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Check availability on Northeast Missouri Spa Hotels

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Northeast Missouri hotels with a spa

A wooden interior with a hot tub, a wheelchair-accessible bench, and a window.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.

1. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
  • Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating spa pool, indoor pool, and hydromassage showers.
AU$133
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
An outdoor patio with tables and chairs, green umbrellas, and string lights.
A spacious lobby with a fireplace, seating area, and large windows.

2. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
  • Revitalising spa treatments await at this hotel, where an indoor pool, cosy pillow menus, and attentive staff create a relaxing retreat.
AU$180
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Quincy East by IHG
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A two-story building with a dark entrance, large windows, and a brick facade.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

3. Truitt Hotel

Truitt Hotel
Lafayette Square
AU$290
includes taxes & fees
25 Oct - 26 Oct
Truitt Hotel
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
AU$246
includes taxes & fees
22 Nov - 23 Nov
21C Museum Hotel St Louis
A spa area with a massage table, a hot tub, and a grill.
A living room with a fireplace, a dining area with a round table, and a balcony with a view.
A row of houses with a driveway leading to a gated entrance.
A hot tub, a fire pit, and a view of a lake.

5. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private spa pools and spa treatments offers romantic rejuvenation.
AU$498
includes taxes & fees
17 Nov - 18 Nov
Hermann Hill
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bakery display case with various pastries and cakes.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
AU$241
includes taxes & fees
22 Nov - 23 Nov
Ameristar Casino Resort and Spa
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A bar area with leather seating, a bar counter, and shelves of bottles.

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
AU$962
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

8. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
AU$624
includes taxes & fees
25 Oct - 26 Oct
Four Seasons Hotel St Louis
View all properties

Choose what matters most at spa hotels in Northeast Missouri

Pool
Breakfast included
Spa pool
4 stars
5 stars

Spa hotels with free breakfast in Northeast Missouri

A hotel room with a bed, a sofa, a desk, and a lamp.
A restaurant with multiple tables and chairs, an exit sign, and a counter area.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
AU$133
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
An outdoor patio with tables and chairs, green umbrellas, and string lights.
A spacious lobby with a fireplace, seating area, and large windows.

Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
AU$180
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Quincy East by IHG
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."

21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
AU$246
includes taxes & fees
22 Nov - 23 Nov
21C Museum Hotel St Louis
A hot tub, a fire pit, and a view of a lake.
A bathroom with a bathtub, a shower, and a vanity with a mirror.
A hotel room with a large bed, a bathtub, and a view of the outdoors.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.

Hermann Hill

Hermann Hill
Hermann
AU$498
includes taxes & fees
17 Nov - 18 Nov
Hermann Hill
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A bar area with leather seating, a bar counter, and shelves of bottles.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A lobby with a fireplace, two armchairs, a round table, and a bench.

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
AU$962
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Northeast Missouri Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Loved the area to the event"
Jorge 3-night trip
Posted 2 hours ago
Pear Tree Inn St. Louis Near Union Station
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Room was quite large and very comfortable."
Barbara 3-night trip
Posted 11 hours ago
Ameristar Casino Resort and Spa
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"The staff were friendly and helpful. It was a wonderful stay a around"
Irma 1-night trip
Posted 1 day ago
Drury Plaza Hotel St. Louis Union Station

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