A large eye sculpture in a park surrounded by trees.

Spa Hotels & Resorts in Northeast Missouri from AU$126

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Check availability on Northeast Missouri Spa Hotels

Tonight
5 Sept - 6 Sept
Tomorrow
6 Sept - 7 Sept
Next weekend
11 Sept - 13 Sept
In two weeks
18 Sept - 20 Sept

Our top choices for Northeast Missouri hotels with a spa

A wooden interior with a hot tub, a wheelchair-accessible bench, and a window.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
A hotel room with a bed, a sofa, a desk, and a lamp.

1. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
  • Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating spa pool, indoor pool, and hydromassage showers.
AU$126
includes taxes & fees
20 Sept - 21 Sept
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
A spacious lobby with a fireplace, seating area, and large windows.

2. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
  • Revitalising spa treatments await at this hotel, where an indoor pool, cosy pillow menus, and attentive staff create a relaxing retreat.
AU$201
includes taxes & fees
20 Sept - 21 Sept
Holiday Inn Quincy East by IHG
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A well-lit lobby with a chandelier, seating area, and decorative plants.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.

3. Truitt Hotel

Truitt Hotel
Lafayette Square
AU$283
includes taxes & fees
14 Sept - 15 Sept
Truitt Hotel
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

4. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
AU$277
includes taxes & fees
22 Sept - 23 Sept
Ameristar Casino Resort and Spa
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

5. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
AU$240
includes taxes & fees
4 Oct - 5 Oct
21C Museum Hotel St Louis
A spa area with a massage table, a hot tub, and a grill.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.
A row of houses with a driveway leading to a gated entrance.
A hot tub, a fire pit, and a view of a lake.

6. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private spa pools and spa treatments offers romantic rejuvenation.
AU$534
includes taxes & fees
28 Sept - 29 Sept
Hermann Hill
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
A couple standing on a balcony with a cityscape view.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
AU$890
includes taxes & fees
20 Sept - 21 Sept
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern hotel lobby with a glass facade, seating area, and a staircase.

8. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
AU$609
includes taxes & fees
16 Sept - 17 Sept
Four Seasons Hotel St Louis
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Choose what matters most at spa hotels in Northeast Missouri

Pool
Breakfast included
Spa pool
4 stars
5 stars

Spa hotels with free breakfast in Northeast Missouri

A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
A spacious lobby with a fireplace, seating area, and large windows.

Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
AU$201
includes taxes & fees
20 Sept - 21 Sept
Holiday Inn Quincy East by IHG
A hotel room with a bed, a sofa, a desk, and a lamp.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
A restaurant with multiple tables and chairs, an exit sign, and a counter area.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
AU$126
includes taxes & fees
20 Sept - 21 Sept
Comfort Inn & Suites - Hannibal
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
An indoor swimming pool with a 'SWIM FOR LIFE' sign, surrounded by patterned walls and windows.

21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
AU$240
includes taxes & fees
4 Oct - 5 Oct
21C Museum Hotel St Louis
A hot tub, a fire pit, and a view of a lake.
A row of houses with a driveway leading to a gated entrance.
A hotel room with a large bed, a bathtub, and a view of the outdoors.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.

Hermann Hill

Hermann Hill
Hermann
AU$534
includes taxes & fees
28 Sept - 29 Sept
Hermann Hill
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A modern living room with a sofa, chairs, a coffee table, and a chandelier.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A bar area with leather seating, a bar counter, and shelves of bottles.

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
AU$890
includes taxes & fees
20 Sept - 21 Sept
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Northeast Missouri Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"Good stay and good breakfast!"
Lindsey 1-night trip
Posted 2 hours ago
Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Very easy check in. Friendly staff. Rooms were clean and maintained throughout our stay. Amenities were great. Parking was awesome! And free"
Gena 2-night trip
Posted 7 hours ago
Pear Tree Inn St. Louis Near Union Station
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good
"Room was clean Pillows not comfy There was no cold water-odd as no hot water is the common problem with water but too hot to take a shower !!!"
Mary 1-night trip
Posted 9 hours ago
Ameristar Casino Resort and Spa

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