Search Muscatine hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
2 Dec - 3 Dec
Tomorrow
3 Dec - 4 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Filter by

Guest rating
Guest rating
Star rating

Top hotels and accommodation in Muscatine

Indoor pool
AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine

2.5 star property
Muscatine
7.6 out of 10, Good, (421)
"The check in process was smooth & I was checked into my room quick "
United States
Dalvin
The price is AU$138
includes taxes & fees
3 Dec - 4 Dec
AmericInn by Wyndham Muscatine
Reception
Hampton Inn Muscatine

Hampton Inn Muscatine

2.5 star property
Muscatine
8.4 out of 10, Very good, (462)
"Nice stay"
United States
Bradlee Dean
The price is AU$156
includes taxes & fees
11 Dec - 12 Dec
Hampton Inn Muscatine
Suite, Multiple Beds, Non Smoking
Comfort Inn Muscatine near Hwy 61

Comfort Inn Muscatine near Hwy 61

2.5 star property
Muscatine
7.8 out of 10, Good, (214)
"Nice clean good bed"
United States
John W
The price is AU$109
includes taxes & fees
27 Dec - 28 Dec
Comfort Inn Muscatine near Hwy 61
Exterior
Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel

2.5 star property
Muscatine
8.6 out of 10, Excellent, (496)
"It was nice for the money. Staff was very friendly. "
United States
Nichole
The price is AU$154
includes taxes & fees
4 Dec - 5 Dec
Best Western Muscatine / Pearl City Hotel
Breakfast, lunch, dinner served; American cuisine
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

4.0 star property
Muscatine
9.6 out of 10, Exceptional, (277)
"Great Hotel. The restaurant, Maxwell's was very good."
United States
Dennis
The price is AU$333
includes taxes & fees
22 Dec - 23 Dec
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
Reception
The Sage Hotel

The Sage Hotel

2.0 star property
Muscatine
6.8 out of 10, (55)
"Awesome "
United States
Dauda
The Sage Hotel
Free daily on-the-go breakfast
Super 8 by Wyndham Muscatine

Super 8 by Wyndham Muscatine

2.0 star property
Muscatine
6.2 out of 10, (276)
"Staff was nice, let me check in a little early, quiet, comfortable bed."
United States
Mark
The price is AU$109
includes taxes & fees
3 Dec - 4 Dec
Super 8 by Wyndham Muscatine
Lobby
Hyatt House East Moline Quad Cities

Hyatt House East Moline Quad Cities

3.0 star property
East Moline
9.2 out of 10, Wonderful, (1022)
"The room was very clean and the staff were amazing. The view of the river was very relaxing as well. "
United States
Dara
The price is AU$158
includes taxes & fees
7 Dec - 8 Dec
Hyatt House East Moline Quad Cities
Exterior
Wyndham Moline on John Deere Commons

Wyndham Moline on John Deere Commons

3.5 star property
Moline
9.0 out of 10, Wonderful, (1225)
"Clean room , breakfast was great "
United States
Charles
The price is AU$151
includes taxes & fees
21 Dec - 22 Dec
Wyndham Moline on John Deere Commons
Lobby
Quality Inn & Suites Moline - Quad Cities

Quality Inn & Suites Moline - Quad Cities

2.5 star property
Moline
7.6 out of 10, Good, (552)
"Room was good. staff was very helpful. good stay in a convenient location"
United States
Mark
The price is AU$82
includes taxes & fees
25 Dec - 26 Dec
Quality Inn & Suites Moline - Quad Cities
Mini fridge
La Quinta Inn by Wyndham Davenport & Conference Center

La Quinta Inn by Wyndham Davenport & Conference Center

3.0 star property
Davenport
7.4 out of 10, Good, (1016)
"Was a good place to stay"
United States
Ed
The price is AU$98
includes taxes & fees
1 Jan - 2 Jan 2026
La Quinta Inn by Wyndham Davenport & Conference Center
Meeting facility
Hyatt Place East Moline Quad Cities

Hyatt Place East Moline Quad Cities

3.0 star property
East Moline
9.2 out of 10, Wonderful, (984)
"Excellent condition, friendly staff, great rooftop bar."
United States
David
The price is AU$173
includes taxes & fees
4 Dec - 5 Dec
Hyatt Place East Moline Quad Cities
Suite, 1 Bedroom, Non Smoking (1 King Bed)
Days Inn By Wyndham Davenport

Days Inn By Wyndham Davenport

2.0 star property
Davenport
8.0 out of 10, Very good, (368)
"Very friendly staff. Wonderful bed. Nice and quiet. Great value!!!!!!"
United States
Mary
The price is AU$92
includes taxes & fees
8 Dec - 9 Dec
Days Inn By Wyndham Davenport
Exterior
The Axis Moline Hotel, Tapestry Collection by Hilton

The Axis Moline Hotel, Tapestry Collection by Hilton

3.5 star property
Moline
9.4 out of 10, Exceptional, (388)
"Great stay."
United States
John
The price is AU$225
includes taxes & fees
8 Dec - 9 Dec
The Axis Moline Hotel, Tapestry Collection by Hilton
Exterior
La Quinta Inn by Wyndham Moline Airport

La Quinta Inn by Wyndham Moline Airport

3.0 star property
Moline
6.4 out of 10, (1004)
"The staff was really nice"
United States
jason
The price is AU$81
includes taxes & fees
7 Dec - 8 Dec
La Quinta Inn by Wyndham Moline Airport
Business centre
Best Western Airport Inn

Best Western Airport Inn

2.5 star property
Moline
8.2 out of 10, Very good, (1002)
"Comfortable place to stay and great management thank you "
United States
Jason
The price is AU$102
includes taxes & fees
7 Dec - 8 Dec
Best Western Airport Inn
Room, 1 King Bed, Accessible, Non Smoking
Comfort Inn Davenport East - Bettendorf

Comfort Inn Davenport East - Bettendorf

2.5 star property
Davenport
9.4 out of 10, Exceptional, (162)
"Clean room, comfortable beds, very friendly staff, very affordable. "
United States
Alicia
The price is AU$111
includes taxes & fees
18 Dec - 19 Dec
Comfort Inn Davenport East - Bettendorf
Standard Room, 2 Queen Beds
Days Inn & Suites by Wyndham Davenport East

Days Inn & Suites by Wyndham Davenport East

2.5 star property
Davenport
7.6 out of 10, Good, (1008)
"Good room for a good price."
United States
Mike
The price is AU$94
includes taxes & fees
3 Dec - 4 Dec
Days Inn & Suites by Wyndham Davenport East
Exterior
Stoney Creek Hotel Quad Cities - Moline

Stoney Creek Hotel Quad Cities - Moline

2.5 star property
Moline
8.4 out of 10, Very good, (1092)
"Breakfast was hot and fresh comfy rooms "
United States
Alena
The price is AU$131
includes taxes & fees
1 Jan - 2 Jan 2026
Stoney Creek Hotel Quad Cities - Moline
Lobby
Sleep Inn & Suites Davenport - Quad Cities

Sleep Inn & Suites Davenport - Quad Cities

2.5 star property
Davenport
8.2 out of 10, Very good, (952)
"Great location for our trip!"
United States
Lori
The price is AU$115
includes taxes & fees
21 Dec - 22 Dec
Sleep Inn & Suites Davenport - Quad Cities
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Muscatine attractions

Another rustic window on the Pine Creek Grist Mill at Wildcat Den State Park.
Photo by Bill Eaker
Open Photo by Bill Eaker

Wildcat Den State Park

You can take time to visit Wildcat Den State Park during your travels to Muscatine. Make time to visit the monuments and churches while you're in the area.
See properties
Iowa, heartland, fall, train trestle, railroad tracks, river, clouds, sky, blue, fields, rivers, midwest, views

Riverside Park

4.0/5 (42 reviews)
Explore the great outdoors at Riverside Park, a lovely green space in Muscatine. Discover the area's entertainment choices and churches.
See properties

Learn more about Muscatine

Stroll along the Mississippi riverfront to spot bald eagles and watch riverboats glide by. Explore local history at the Pearl Button Museum, then sample wines at the family-owned Ardon Creek Winery.

See all hotels in Muscatine
Confluence of Mississippi and Wisconsin Rivers, Iowa

Top Muscatine Hotel Reviews

Recent Reviews in Muscatine

Wyndham Moline on John Deere Commons

Wyndham Moline on John Deere Commons

10/10 Excellent
"Nice clean lobby. Welcoming "
Laurie 4-night trip
Posted 2 days ago
Wyndham Moline on John Deere Commons

More cheap accommodation in Muscatine

More cheap accommodation in Muscatine

Stoney Creek Hotel Quad Cities - Moline

Stoney Creek Hotel Quad Cities - Moline

101 18th St Moline IL
The price is AU$131 per night from 1 Jan to 2 Jan
AU$131
1 Jan - 2 Jan 2026
includes taxes & fees
8.2/10 Very Good! (1,091 reviews)

Frequently asked questions

What's the best place for a stay in Muscatine?
Strawberry Farm Bed & Breakfast is a favourite with Expedia customers. This B&B offers free breakfast and free parking. Reviews from our site also recommend Hampton Inn Muscatine and Best Western Muscatine / Pearl City Hotel as top choices for your stay. See all available top hotels, or vacation rentals in Muscatine.
What are some of the best holiday rentals that Muscatine has to offer?
Lucy's House Single Family Bungalow: This holiday home rental outside of Muscatine is located on a river, and has a patio, a garden and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. Make the most of books in this rental home to help you unwind. See all vacation rentals in Muscatine.
If I need to cancel my hotel reservation in Muscatine, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Muscatine.
What's the best family accommodation in Muscatine?
Super 8 by Wyndham Muscatine is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel is another good choice for your child-friendly holiday. Also, children of all ages will enjoy a visit to Muscatine Aquatic Center. Find more child-friendly accommodations in Muscatine.
What's the best LGBTQ-friendly hotel in Muscatine?
Hampton Inn Muscatine is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel is another good option for your stay. See all available hotels listed as LGBTQ-friendly in Muscatine.
What's the best dog-friendly accommodation option in Muscatine?
AmericInn by Wyndham Muscatine is a top dog-friendly hotel, and offers an indoor pool along with free WiFi for its human guests. Other good options to stay with your pet include Hampton Inn Muscatine and Best Western Muscatine / Pearl City Hotel. See more pet-friendly hotel accommodations in Muscatine.
What are some accommodation options with pools in Muscatine?
Best Western Muscatine / Pearl City Hotel: Features buffet, an indoor pool and free self parking. AmericInn by Wyndham Muscatine and The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel are a couple of other choices that feature an on-site pool. View all hotels with pools in Muscatine.
What is staying in Muscatine like?
Visitors can enjoy all that Muscatine has to offer, including the riverfront, baseball games and theatres. Tourists can also enjoy the city's entertainment choices, monuments and churches. In Muscatine, there are 16 hotels and other accommodation options to choose from. Find out more about Muscatine.
What is there to see in Muscatine?
The picturesque setting of Mississippi River and Cedar River exemplify the area's natural beauty. A couple of additional sights to add to your itinerary are Wildcat Den State Park and Pine Creek Grist Mill. Take a look at what more there is to see and do in Expedia's Muscatine guide.
What's the weather like in Muscatine?
The hottest months are usually July and August, with an average temperature of 22°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Muscatine are January, November, February and December, with each month seeing an average of 18 cm of snowfall.

Explore a world of travel with Expedia