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Check prices for these dates

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9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Top hotels and accommodation in Mesopotamia

Interior
To Spiti tis Sofias

To Spiti tis Sofias

Kastoria
10.0 out of 10, Exceptional, (1)
"Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. "
France
Anonymous traveller
The price is AU$115
includes taxes & fees
8 Jan - 9 Jan 2026
To Spiti tis Sofias
3 restaurants, breakfast, lunch, dinner served; Greek cuisine
Limneon Resort & Spa

Limneon Resort & Spa

4.0 star property
Kastoria
9.2 out of 10, Wonderful, (197)
"Wonderful stay. "
Canada
Konstantinos
The price is AU$165
includes taxes & fees
18 Dec - 19 Dec
Limneon Resort & Spa
Free daily buffet breakfast
Chloe Hotel

Chloe Hotel

3.0 star property
Kastoria
10.0 out of 10, Exceptional, (86)
"We enjoyed the stay, friendly staff and nice breakfast "
Australia
Fani
The price is AU$169
includes taxes & fees
9 Jan - 10 Jan 2026
Chloe Hotel
Property grounds
Calma Hotel & Spa

Calma Hotel & Spa

4.0 star property
Kastoria
9.6 out of 10, Exceptional, (35)
"Pleasant stay. Good amenities. Great staff. "
New Zealand
Robert
Calma Hotel & Spa
Front of property – evening/night
Hotel Anastassiou

Hotel Anastassiou

2.0 star property
Kastoria
8.0 out of 10, Very good, (69)
"Nice simple stay."
United States
Jeffrey
Hotel Anastassiou
Breakfast, lunch and dinner served
Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel

4.0 star property
Kastoria
9.0 out of 10, Wonderful, (84)
"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. "
United States
Michal
Esperos Palace Luxury & Spa Hotel
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Kyknos De Luxe Hotel

Kyknos De Luxe Hotel

Kastoria
10.0 out of 10, Exceptional, (43)
"Very nice clean, very polite staff and great breakfast!"
United States
Vasilios
The price is AU$157
includes taxes & fees
11 Dec - 12 Dec
Kyknos De Luxe Hotel
Garden
Guesthouse Vissinokipos

Guesthouse Vissinokipos

Kastoria
9.4 out of 10, Exceptional, (10)
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
United States
Carmen
Guesthouse Vissinokipos
Exterior
Guest House Ilektra

Guest House Ilektra

Voio
9.6 out of 10, Exceptional, (9)
"Wonderful views, easy to find, spacious rooms, and great hospitality."
United Kingdom
Maria
The price is AU$103
includes taxes & fees
10 Dec - 11 Dec
Guest House Ilektra
Exterior
Andromeda Boutique hotel

Andromeda Boutique hotel

4.0 star property
Kastoria
8.8 out of 10, Excellent, (3)
Andromeda Boutique hotel
Room amenity
Guesthouse Monopati

Guesthouse Monopati

Amyntaio
10.0 out of 10, Exceptional, (3)
Guesthouse Monopati
Property grounds
Anesis Hotel

Anesis Hotel

2.0 star property
Kastoria
9.0 out of 10, Wonderful, (9)
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
Canada
Adam
The price is AU$94
includes taxes & fees
17 Dec - 18 Dec
Anesis Hotel
House
Anastasia s Kastoria Cozy Modern Garden Retreat

Anastasia s Kastoria Cozy Modern Garden Retreat

Kastoria
The price is AU$184
includes taxes & fees
10 Dec - 11 Dec
Anastasia s Kastoria Cozy Modern Garden Retreat
Apartment
The Sunset Haven Kastoria Modern Lake Elegance

The Sunset Haven Kastoria Modern Lake Elegance

Kastoria
The price is AU$261
includes taxes & fees
10 Dec - 11 Dec
The Sunset Haven Kastoria Modern Lake Elegance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesopotamia Hotel Reviews

Recent Reviews in Mesopotamia

Limneon Resort & Spa

Limneon Resort & Spa

10/10 Excellent
"Excellent! "
Mel 7-night trip
Posted 3 months ago
Limneon Resort & Spa

More cheap accommodation in Mesopotamia

Hotel Anastassiou

Hotel Anastassiou

1st km Highway Kastoria-Athens Kastoria Western Macedonia
Get rates
7.8/10 Good! (69 reviews)

Frequently asked questions

Where is the best place for a stay in Mesopotamia?
To Spiti tis Sofias is one of the top choices for your stay based on our traveller data. This guest house offers free parking and free WiFi. Two other choices for your stay in the area are Limneon Resort & Spa and Hotel Anastassiou. See all available top hotels, or vacation rentals in Mesopotamia.
What are some of the best holiday rentals that Mesopotamia has to offer?
The Sunset Haven Kastoria Modern Lake Elegance: This holiday home rental outside of Mesopotamia offers a BBQ and free WiFi to help you feel comfortable in your new surroundings. See all vacation rentals in Mesopotamia.
If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.
What is staying in Mesopotamia like?
Travellers to Mesopotamia will find plenty to explore and enjoy. There are 44 hotels and other accommodation options in the surrounding area. Find out more about Mesopotamia.
What are the top places to visit in Mesopotamia?
Places to visit in the wider area include Kastoria Aquarium, Kastoria Lake and Neolithic Lakeside Settlement. You'll also find Folklore Museum of Kastoria and Byzantine Museum of Kastoria in the area. Take a look at what more there is to see and do in Expedia's Mesopotamia guide.
What's the seasonal weather like in Mesopotamia?
The hottest months are usually August and July, with an average temperature of 20°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Mesopotamia is 707 mm.

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