Search Mesilla hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Top hotels and accommodation in Mesilla

Exterior
Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

2.5 star property
Las Cruces
8.2 out of 10, Very good, (1274)
"Friendly staff and spacious King room."
United States
Donald
The price is AU$87
includes taxes & fees
14 Dec - 15 Dec
Days Inn by Wyndham Las Cruces
Lobby
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

3.0 star property
Las Cruces
8.2 out of 10, Very good, (2283)
"Staff was lovely. Room is dated but had a great view."
United States
Patricia
The price is AU$98
includes taxes & fees
21 Dec - 22 Dec
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Restaurant
Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25

2.5 star property
Las Cruces
8.4 out of 10, Very good, (1006)
"Room and service were great"
United States
Shaun
The price is AU$150
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Las Cruces I-25
Desk, laptop workspace, blackout curtains, soundproofing
Super 8 by Wyndham Las Cruces/White Sands Area

Super 8 by Wyndham Las Cruces/White Sands Area

2.0 star property
Las Cruces
7.2 out of 10, Good, (1002)
"Was a place to rest my head during my travels for a night so affordable & room was in good condition. "
United States
Gloria
The price is AU$86
includes taxes & fees
4 Jan - 5 Jan 2026
Super 8 by Wyndham Las Cruces/White Sands Area
Exterior
Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG

2.5 star property
Las Cruces
9.0 out of 10, Wonderful, (977)
"It was nice stay "
United States
Rajesh
The price is AU$207
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Las Cruces North by IHG
Property amenity
Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1008)
"Clean room, good breakfast, nice staff, and great pricing. "
United States
Shahzad
The price is AU$164
includes taxes & fees
14 Dec - 15 Dec
Drury Inn & Suites Las Cruces
Restaurant
Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10

2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1005)
"I recommend Studio Suite; it's huge, very clean, has a very varied and delicious breakfast, and the staff is very friendly."
United States
Nora
The price is AU$162
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Las Cruces I-10
Property amenity
Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces

3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1005)
"Great stay"
United States
Myles
The price is AU$143
includes taxes & fees
22 Dec - 23 Dec
Hilton Garden Inn Las Cruces
Exterior
Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG

3.0 star property
Las Cruces
8.8 out of 10, Excellent, (1001)
"The room was very clean, and even though it was thanksgiving the staff was very nice and helpful. The breakfast was good too. I would definitely stay here again"
United States
Raul
The price is AU$166
includes taxes & fees
14 Dec - 15 Dec
Staybridge Suites Las Cruces by IHG
Indoor pool
Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North

2.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1003)
"We stay here every time we are coming through Las Cruces. This hotel always meets our expectations. "
United States
John
The price is AU$197
includes taxes & fees
14 Dec - 15 Dec
Comfort Suites Las Cruces I-25 North
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers
Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces

3.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1588)
"We had a wonderful stay. "
United States
Amber
The price is AU$227
includes taxes & fees
21 Dec - 22 Dec
Hotel Encanto de Las Cruces
Lobby
Comfort Suites University Las Cruces

Comfort Suites University Las Cruces

2.5 star property
Las Cruces
8.0 out of 10, Very good, (1004)
"Amazing staff, clean rooms, great breakfast "
United States
Michelle
The price is AU$137
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites University Las Cruces
Indoor pool
Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla

2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1003)
"Nice place"
United States
chris
The price is AU$173
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn & Suites Las Cruces Mesilla
Full-sized fridge, microwave, dishwasher, coffee/tea maker
Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces

3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (654)
"The room is very clean, staff is very friendly. "
United States
Blanca A
The price is AU$187
includes taxes & fees
23 Dec - 24 Dec
Home2 Suites by Hilton Las Cruces
Exterior
La Quinta Inn by Wyndham Las Cruces Mesilla Valley

La Quinta Inn by Wyndham Las Cruces Mesilla Valley

3.0 star property
Las Cruces
5.4 out of 10, (1003)
"This was the worst hotel that have ever stayed at. The whole place was extreamly dirty and smelly. The staff was rude even. This hotel is so bad that it should be shutdown. No one should stay here."
United States
Sergio
The price is AU$104
includes taxes & fees
9 Dec - 10 Dec
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Business centre
Best Western Mission Inn

Best Western Mission Inn

2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1233)
"Very comfortable place to stay"
United States
Maryann
The price is AU$134
includes taxes & fees
14 Dec - 15 Dec
Best Western Mission Inn
Free daily continental breakfast
Holiday Inn Express Hotel and Suites Las Cruces by IHG

Holiday Inn Express Hotel and Suites Las Cruces by IHG

2.5 star property
Las Cruces
7.8 out of 10, Good, (1001)
"Great place to stay. "
United States
Martin and Nancy
The price is AU$186
includes taxes & fees
6 Jan - 7 Jan 2026
Holiday Inn Express Hotel and Suites Las Cruces by IHG
Desk, laptop workspace, iron/ironing board, free WiFi
Extended Stay America Select Suites - Las Cruces

Extended Stay America Select Suites - Las Cruces

2.5 star property
Las Cruces
5.8 out of 10, (437)
"Great spot will be back. "
United States
Michelle
The price is AU$113
includes taxes & fees
8 Dec - 9 Dec
Extended Stay America Select Suites - Las Cruces
Free daily buffet breakfast
Fairfield Inn by Marriott Las Cruces

Fairfield Inn by Marriott Las Cruces

2.5 star property
Las Cruces
8.6 out of 10, Excellent, (510)
"Really good breakfast and helpful staff"
United States
Magdalena
The price is AU$212
includes taxes & fees
14 Dec - 15 Dec
Fairfield Inn by Marriott Las Cruces
Lobby
Sleep Inn University

Sleep Inn University

2.5 star property
Las Cruces
7.6 out of 10, Good, (1002)
"Overall it a nice stay but breakfast could be better"
United States
Joanna
The price is AU$104
includes taxes & fees
28 Dec - 29 Dec
Sleep Inn University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Mesilla attractions

Mesillia Plaza

This National Historic Landmark features preserved 19th-century adobe architecture from the Gadsden Purchase era. Browse unique shops, savour authentic cuisine, and experience cultural events in this historic square.
See properties

Fountain Theater

The Fountain Theatre, New Mexico's oldest continuously operating film house, showcases independent and foreign films in a historic 1905 setting. Enjoy fresh popcorn in this intimate cultural landmark.
See properties

Learn more about Mesilla

Historic adobe buildings surround the plaza where Billy the Kid once stood trial in this charming town. Explore local art galleries and sample authentic Mexican cuisine at La Posta, a restaurant housed in a 19th-century stagecoach stop.

See all hotels in Mesilla
Red chile doorway Mesilla NM

Top Mesilla Hotel Reviews

Recent Reviews in Mesilla

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

10/10 Excellent
"Nice"
Pavlo 1-night trip
Posted 3 days ago
Days Inn by Wyndham Las Cruces

More cheap accommodation in Mesilla

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

755 Avenida De Mesilla Las Cruces NM
The price is AU$87 per night from 14 Dec to 15 Dec
AU$87
14 Dec - 15 Dec
includes taxes & fees
8.2/10 Very Good! (1,271 reviews)

Frequently asked questions

What's the best place for a stay in Mesilla?
Located 4.5 mi (7.3 km) from the heart of Mesilla, Hotel Encanto de Las Cruces is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces. See all available top hotels, or vacation rentals in Mesilla.
What are some of the best holiday rentals that Mesilla has to offer?
Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis: This holiday home rental outside of Mesilla offers a fireplace, a patio and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a stovetop and a microwave, so that you can cook with friends or family. See all vacation rentals in Mesilla.
If I need to cancel my hotel reservation in Mesilla, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesilla.
What are some hotels with pools in Mesilla?
Hotel Encanto de Las Cruces: Hotel located near New Mexico State University. Provides 3 bars, an outdoor pool and a 24-hour fitness centre. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces are two additional hotels that offer an on-site pool. View all hotels with pools in Mesilla.
What is staying in Mesilla like?
Visitors can enjoy all that Mesilla has to offer, including the restaurants, shopping and theatres. In Mesilla, there are 14 hotels and other accommodation options to choose from. Find out more about Mesilla.
What should I do while I'm visiting Mesilla?
Cultural venues include Fountain Theatre and Fountain Theater. Landmarks like Mesillia Plaza and San Albino Basilica might be worth a visit. Additionally, you might want to add Rio Grande to your itinerary. Take a look at what more there is to see and do in Expedia's Mesilla guide.
What's the seasonal weather in Mesilla?
The hottest months are usually June and July, with an average temperature of 28°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Mesilla is 227 mm.

Explore a world of travel with Expedia