Top Hotels Near Main Street Hyannis in Hyannis from AU$118

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Tonight
10 Dec - 11 Dec
Tomorrow
11 Dec - 12 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Main Street Hyannis hotels

Terrace/patio
Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1003)
"Beautiful quaint hotel, with a nice view of the water. The place has a pool, a fire pit and nice spacious rooms. Would stay again. "
United States
Alberto
The price is AU$284
includes taxes & fees
14 Dec - 15 Dec
Anchor In Distinctive Waterfront Lodging
View from room
Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
1.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (97)
"Hotel was quiet and very clean , pool water was cool"
United States
Robyn
The price is AU$183
includes taxes & fees
11 Dec - 12 Dec
Uncommoner Hotel by Reverie Boutique Collection
Lobby lounge
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
2.5 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (656)
"Great people, nice breakfast "
United States
Lorri
The price is AU$174
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1000)
"Excellent stay."
United States
Patricia
The price is AU$178
includes taxes & fees
7 Jan - 8 Jan 2026
Hampton Inn & Suites Cape Cod-West Yarmouth
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Bayside Resort Hotel

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1520)
"excellent quality of food. Pool and hot tub fabulous"
United States
Deborah
Bayside Resort Hotel
View from property
Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (486)
"Pretty nice location"
United States
Saulius
The price is AU$211
includes taxes & fees
5 Jan - 6 Jan 2026
Courtyard By Marriott Cape Cod Hyannis
Exterior
Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
1 km from Main Street Hyannis
8.4 out of 10, Very good, (877)
"Nice room, freindly staff. The downside is the food was pricey. "
United States
Steffanie
The price is AU$196
includes taxes & fees
19 Dec - 20 Dec
Doubletree by Hilton Cape Cod - Hyannis
Exterior
Cape Sands Inn

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1013)
"I love this hotel clean good up keep "
United States
Jerome
The price is AU$118
includes taxes & fees
14 Dec - 15 Dec
Cape Sands Inn
Exterior
Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (976)
"Check in was easy and the front desk person was wonderful. "
United States
Anastasios
The price is AU$184
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Hyannis by IHG
Free daily continental breakfast
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1000)
"Well appointed lodging with very friendly and attentive staff. Perfect central location with easy walk to many local sights as well as convenient access to ferry terminal. "
United States
Kerri
The price is AU$169
includes taxes & fees
16 Dec - 17 Dec
Comfort Inn Hyannis - Cape Cod
Front of property
Hyannis Harbor Hotel

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1003)
"Amazing place "
United States
Mounir
The price is AU$265
includes taxes & fees
11 Dec - 12 Dec
Hyannis Harbor Hotel
Lobby
Hyannis Plaza Hotel

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.0 out of 10, Good, (966)
"good stay for night"
United States
David
The price is AU$138
includes taxes & fees
9 Jan - 10 Jan 2026
Hyannis Plaza Hotel
Indoor pool
Courtyard Resort

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (43)
"Room was very clean. Staff were courteous!"
United States
Timothy
The price is AU$188
includes taxes & fees
17 Dec - 18 Dec
Courtyard Resort
Family House, Private Bathroom, Pool View | Shared kitchen
Sal's Place

Sal's Place

Sal's Place
2.0 star property
2.5 km from Main Street Hyannis
The price is AU$663
includes taxes & fees
11 Dec - 12 Dec
Sal's Place
Outdoor dining
Inn on Main

Inn on Main

Inn on Main
3.5 star property
6.4 km from Main Street Hyannis
10.0 out of 10, Exceptional, (73)
"We love staying here! Best dog B&B in America!"
United States
Barbara
The price is AU$470
includes taxes & fees
14 Dec - 15 Dec
Inn on Main
Property grounds
The Escape Inn

The Escape Inn

The Escape Inn
2.5 star property
7.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (653)
"One of the best hotels I stayed at "
United States
Robert
The price is AU$155
includes taxes & fees
11 Dec - 12 Dec
The Escape Inn
Deluxe Suite, Oceanfront, 2 Bedrooms | Terrace/patio
Ocean Club on Smuggler's Beach

Ocean Club on Smuggler's Beach

Ocean Club on Smuggler's Beach
2.5 star property
6.9 km from Main Street Hyannis
9.2 out of 10, Wonderful, (1000)
"The Ocean Club is always a great place to stay. Very convenient location and a great place for a walk on the beach. "
United States
Steve
The price is AU$273
includes taxes & fees
23 Dec - 24 Dec
Ocean Club on Smuggler's Beach
Outdoor pool, pool umbrellas, pool loungers
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
3.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (412)
"The entire place was spotless and rooom beet pleasant. Staff was super friendly and the Landshark Bar was excellent. Highly recommend a stay here ! "
United States
Stephen
Margaritaville Resort Cape Cod
Oceanfront Efficiency, 1 King Bed
Chatham Tides

Chatham Tides

Chatham Tides
2.5 star property
20.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (665)
"We loved it so much that we will definitely going back. "
United States
Faith
The price is AU$262
includes taxes & fees
16 Dec - 17 Dec
Chatham Tides
BBQ/picnic Area
Sandy Neck Motel

Sandy Neck Motel

Sandy Neck Motel
2.5 star property
12.8 km from Main Street Hyannis
8.8 out of 10, Excellent, (143)
"Loved the area!"
United States
Jessica
Sandy Neck Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Main Street Hyannis Hotel Reviews

Bayside Resort Hotel

Bayside Resort Hotel

10/10 Excellent
"excellent quality of food. Pool and hot tub fabulous"
Deborah 2-night trip
Posted 2 days ago
Bayside Resort Hotel

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts

John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
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Cape Cod Maritime Museum which includes a bay or harbor and signage

Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area or visit its seafood restaurants.
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Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 181 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Courtyard Resort and Comfort Inn Hyannis - Cape Cod.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 181 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Whydah Pirate Museum and Cape Cod Maritime Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. You can enjoy live performances at Cape Cod Melody Tent and Barnstable Performing Arts Center.