Lake Nona Medical City Holidays from AU$1,977

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Your Lake Nona Medical City Holiday

Our Lake Nona Medical City holiday packages are a simple and practical way to plan and book your next adventure. Experience the magic of this unique neighbourhood without the hassle of organising everything yourself. Need ideas about what to see during your trip to Lake Nona Medical City? University of Central Florida College of Medicine and Sanford-Burnham Medical Research Institute are two nearby attractions to stick on your to-do list. Don't just dream it — turn it into a reality! Lock in your perfect Lake Nona Medical City holiday with Expedia and experience travel your way.

Top Holiday Package Deals in Lake Nona Medical City

Price found within the past 48 hours. Click for updated prices.
The Delaney Hotel

The Delaney Hotel

3.5 out of 5
South Orange
Price was AU$2,833, price is now AU$1,977 per person
AU$1,977
per person
1 Apr - 8 Apr
found 4 hours ago
Return flight included
Manchester (MAN) to Orlando (MCO)
9.6/10 Exceptional! (1,002 reviews)
Clean room, friendly staff, great brunch downstairs

Reviewed on 17 Jan 2026

Vista Cay by Orlando Resort Rentals on Universal Boulevard

Vista Cay by Orlando Resort Rentals on Universal Boulevard

3.5 out of 5
Price was AU$3,288, price is now AU$2,381 per person
AU$2,381
per person
1 Apr - 8 Apr
found 4 hours ago
Return flight included
Manchester (MAN) to Orlando (MCO)
9.4/10 Exceptional! (843 reviews)
The room was very spacious and clean. There was plenty of room for a family of 5. The pool area was great and the pool was well heated for January as well as the hot tub. It was a nice quiet safe area and a convenient location. We had a few minor concerns and the staff was quick to respond and did everything they could do to help immediately.

Reviewed on 19 Jan 2026

Vista Cay Resort by Millenium at Universal Blvd

Vista Cay Resort by Millenium at Universal Blvd

3.5 out of 5
Price was AU$3,001, price is now AU$2,188 per person
AU$2,188
per person
1 Apr - 8 Apr
found 4 hours ago
Return flight included
Manchester (MAN) to Orlando (MCO)
8.6/10 Excellent! (1,568 reviews)
The property was perfectly located near parks, shopping and restaurants. I loved how it had a nice walking path by the lake and walkable to Publix. The room needed a few repairs and needed a deep clean but the staff did what they could to resolve any issues as quickly as possible. Would stay here again.

Reviewed on 16 Dec 2025

Aster Cove

Aster Cove

4 out of 5
Crescent Lakes
Price was AU$3,418, price is now AU$2,588 per person
AU$2,588
per person
1 Apr - 8 Apr
found 4 hours ago
Return flight included
Manchester (MAN) to Orlando (MCO)
No reviews
Florida Hotel & Conference Center in the Florida Mall

Florida Hotel & Conference Center in the Florida Mall

3.5 out of 5
Price was AU$2,807, price is now AU$2,125 per person
AU$2,125
per person
1 Apr - 8 Apr
found 4 hours ago
Return flight included
Manchester (MAN) to Orlando (MCO)
9.2/10 Wonderful! (2,232 reviews)
We love staying here! The hotel is very clean, staff is amazing, and its so fun to be right in the mall! 20 min drive to Disney!

Reviewed on 19 Jan 2026

Our guide on where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
International Drive showing landscape views

International Drive District

1 out of top 10 points of interest in this area

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Find hotels in International Drive District

Our pick of the best Lake Nona Medical City Hotel Deals

DoubleTree by Hilton Hotel Orlando at SeaWorld

DoubleTree by Hilton Hotel Orlando at SeaWorld

4 out of 5
10100 International Drive Orlando FL
Fully refundableReserve now, pay when you stay
The price is AU$153 per night from 8 Feb to 9 Feb
AU$153
8 Feb - 9 Feb
includes taxes & fees
7.4/10 Good! (6,404 reviews)
The breakfast is good. The environment is quite.

Reviewed on 18 Jan 2026

DoubleTree by Hilton Hotel Orlando at SeaWorld
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4 out of 5
8800 Vistana Centre Dr Orlando FL
Fully refundableReserve now, pay when you stay
The price is AU$224 per night from 22 Jan to 23 Jan
AU$224
22 Jan - 23 Jan
includes taxes & fees
9.2/10 Wonderful! (4,335 reviews)
Everything was awesome, room super comfortable and clean, amenities like brand new, about the staff are simply perfect !

Reviewed on 16 Jan 2026

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
Rosen Inn at Pointe Orlando

Rosen Inn at Pointe Orlando

3 out of 5
9000 International Drive Orlando FL
Fully refundableReserve now, pay when you stay
The price is AU$121 per night from 11 Feb to 12 Feb
AU$121
11 Feb - 12 Feb
includes taxes & fees
8.4/10 Very Good! (5,570 reviews)
A nice room for the value. Very safe, and very quiet.

Reviewed on 20 Jan 2026

Rosen Inn at Pointe Orlando
See all 27,445 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Lake Nona Medical City holiday package cost?
The cheapest Lake Nona Medical City package is AU$1,977, so your dream trip can become a reality — without burning a hole in your pocket. Combine flights, hotels and car rentals to tailor make a package that suits your travel style.
How do I get a cheap travel package to Lake Nona Medical City?
Find flights that fit your busy schedule, add a hotel to your booking and watch the savings rack up with a Lake Nona Medical City holiday package. It's as easy as that! From flights and hotels to tours and rental cars, Expedia makes travelling cheap and easy. And with more than 550 air carriers and 1 000 000 hotel options globally to pick from, you won't be short of choice.
Where should I stay in Lake Nona Medical City?
With loads to explore in Lake Nona Medical City, it'd be convenient for you to stay close to its attractions. Nemours Childrens Hospital, VA Medical Centre at Lake Nona and University of Central Florida College of Medicine are some fascinating ones to add to your to-do list.
What are the top hotels in Lake Nona Medical City?
Make a reservation at Residence Inn Orlando Lake Nona. It's one of the area's most sought-after properties. Another reputable option in Lake Nona Medical City is Courtyard Orlando Lake Nona.
How far in advance should I book my Lake Nona Medical City holiday?
It depends on the airline, but you can generally look up international fares on Expedia up to a year in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally score a cheaper ticket just weeks prior to the date of departure.
What does an Expedia Lake Nona Medical City travel package include?
Expedia has everything you need to organise your Lake Nona Medical City getaway, but what goes into your package is totally up to you. Choose from a combination of hotels, rental cars and flights. In search of some experiences or tours to keep you busy? Once you've made your booking, you can add them too. Whatever your budget or style, there's a deal to match your needs.
What should I know before booking a Lake Nona Medical City travel package?
Locking in all the parts of your escape together is a great way to save. Combine your airfares, rental cars and hotels into one package. But hotels aren't your only option. Expedia has all types of properties, including holiday homes like beachside villas and city apartments. The list goes on!
Can I choose my airline with a Lake Nona Medical City Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our holiday packages give you the freedom to take your pick of available flight, hotel or activity options that fit your needs.
If I'm not able to travel, can I cancel my Lake Nona Medical City holiday package?
Don't worry if you're rethinking your Lake Nona Medical City holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur a fee from your airline, hotel or car rental company. We know life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Activities

MCO Orlando International Airport: Plaza Premium Lounge

MCO Orlando International Airport: Plaza Premium Lounge

AU$91
per adult
MCO Orlando International Airport: Plaza Premium Lounge
Kennedy Space Center Day Experience Transportation from Orlando

Kennedy Space Center Day Experience Transportation from Orlando

AU$118
per adult
Kennedy Space Center Day Experience Transportation from Orlando
14 Passengers Van Airport to or from Port Canaveral One Way

11 Passengers Van Orlando Airport to Port Canaveral One Way

AU$381
per traveller
11 Passengers Van Orlando Airport to Port Canaveral One Way
See all activities in Orlando
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.