Lake Nona Medical City Holidays

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Your Lake Nona Medical City Holiday

Our Lake Nona Medical City holiday packages are a simple and practical way to plan and book your next adventure. Experience the magic of this unique neighbourhood without the hassle of organising everything yourself. Need ideas about what to see during your trip to Lake Nona Medical City? University of Central Florida College of Medicine and Sanford-Burnham Medical Research Institute are two nearby attractions to stick on your to-do list. Don't just dream it — turn it into a reality! Lock in your perfect Lake Nona Medical City holiday with Expedia and experience travel your way.

Our guide on where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
International Drive District

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Find hotels in International Drive District

Our pick of the best Lake Nona Medical City Hotel Deals

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4 out of 5
8800 Vistana Centre Dr Orlando FL
Fully refundableReserve now, pay when you stay
The price is AU$210 per night from 14 May to 15 May
AU$210
14 May - 15 May
includes taxes & fees
9.2/10 Wonderful! (5,323 reviews)
While we were only there for 1 night, it was a great place to stay. The rooms are amazing and it was perfect for any family. Both the bed and sofabed were amazingly comfortable. The ONLY downside is if you like a firmer pillow, bring one as I felt they were almost too soft.

Reviewed on 29 Apr 2026

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

3.5 out of 5
6550 Adventure Way Orlando FL
Fully refundableReserve now, pay when you stay
The price is AU$210 per night from 31 May to 1 June
AU$210
31 May - 1 June
includes taxes & fees
9/10 Wonderful! (6,727 reviews)
Fabulous

Reviewed on 29 Apr 2026

Universal's Cabana Bay Beach Resort
DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

4 out of 5
5780 Major Blvd Orlando FL
Fully refundableReserve now, pay when you stay
The price is AU$160 per night from 31 May to 1 June
AU$160
31 May - 1 June
includes taxes & fees
8.4/10 Very Good! (6,893 reviews)
The pool was wonderful and the room was very clean

Reviewed on 29 Apr 2026

DoubleTree by Hilton at the Entrance to Universal Orlando
See all 27,631 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
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beach holidays
Beach Holidays
Beach Holidays

Frequently asked questions

How much does a Lake Nona Medical City holiday package cost?
The cheapest Lake Nona Medical City package is , so your dream trip can become a reality — without burning a hole in your pocket. Combine flights, hotels and car rentals to tailor make a package that suits your travel style.
How do I get a cheap travel package to Lake Nona Medical City?
Find flights that fit your busy schedule, add a hotel to your booking and watch the savings rack up with a Lake Nona Medical City holiday package. It's as easy as that! From flights and hotels to tours and rental cars, Expedia makes travelling cheap and easy. And with more than 550 air carriers and 1 000 000 hotel options globally to pick from, you won't be short of choice.
Where should I stay in Lake Nona Medical City?
With loads to explore in Lake Nona Medical City, it'd be convenient for you to stay close to its attractions. Nemours Childrens Hospital, VA Medical Centre at Lake Nona and University of Central Florida College of Medicine are some fascinating ones to add to your to-do list.
What are the top hotels in Lake Nona Medical City?
Make a reservation at Residence Inn Orlando Lake Nona. It's one of the area's most sought-after properties. Another reputable option in Lake Nona Medical City is Courtyard Orlando Lake Nona.
How far in advance should I book my Lake Nona Medical City holiday?
It depends on the airline, but you can generally look up international fares on Expedia up to a year in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally score a cheaper ticket just weeks prior to the date of departure.
What does an Expedia Lake Nona Medical City travel package include?
Expedia has everything you need to organise your Lake Nona Medical City getaway, but what goes into your package is totally up to you. Choose from a combination of hotels, rental cars and flights. In search of some experiences or tours to keep you busy? Once you've made your booking, you can add them too. Whatever your budget or style, there's a deal to match your needs.
What should I know before booking a Lake Nona Medical City travel package?
Locking in all the parts of your escape together is a great way to save. Combine your airfares, rental cars and hotels into one package. But hotels aren't your only option. Expedia has all types of properties, including holiday homes like beachside villas and city apartments. The list goes on!
Can I choose my airline with a Lake Nona Medical City Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our holiday packages give you the freedom to take your pick of available flight, hotel or activity options that fit your needs.
If I'm not able to travel, can I cancel my Lake Nona Medical City holiday package?
Don't worry if you're rethinking your Lake Nona Medical City holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur a fee from your airline, hotel or car rental company. We know life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Discover the most popular places to visit in Lake Nona Medical City

Walt Disney World® Resort

Walt Disney World® Resort

Walt Disney World® Resort is part of Orlando. It makes up part of bustling metropolis that is home to 240,000 inhabitants. Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando’s city center. If you are flying in, Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando International Airport.

Walt Disney World® Resort
Universal Studios Florida

Universal Studios Florida

Exhilarating rides and world class film sets are brought together to create this outstanding world-renowned theme park.

Universal Studios Florida
Universal Orlando Resort

Universal Orlando Resort

Make your Florida vacation one to remember with a stay at this hotel and theme park complex.

Universal Orlando Resort

Activities

Rock Hard Revue | The #1 Male Revue in Fl - Preferred Seating

Rock Hard Revue | The #1 Male Revue in Fl - Preferred Seating

AU$61
per adult
Rock Hard Revue | The #1 Male Revue in Fl - Preferred Seating
1 Hour Everglades Airboat Tour Orlando Florida

1 Hour Everglades Airboat Tour Orlando Florida

AU$95
per adult
100% of travellers recommend
1 Hour Everglades Airboat Tour Orlando Florida
Rock Hard Revue | The #1 Male Revue in Fl | General Admission

Rock Hard Revue | The #1 Male Revue in Fl | General Admission

AU$35
per adult
Rock Hard Revue | The #1 Male Revue in Fl | General Admission
See all activities in Orlando
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.