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Our top choices for La Mesa hotels

Lofts Independencia Sayula

Lofts Independencia Sayula
2.0 star property
Sayula
5.6 out of 10, (4)
"Not satisfied charges for parking, pool and needed to ask for fresh towels n toilet paper no AC"
United States
ARTURO
The price is AU$62
includes taxes & fees
20 Jan - 21 Jan 2026
Lofts Independencia Sayula

Capital O Colón, Ciudad Guzmán Jalisco

Capital O Colón, Ciudad Guzmán Jalisco
2.5 star property
Zapotlán el Grande
6.8 out of 10, (156)
"Very nice hotel, nice pool, easy to get to the center and clean"
Canada
Alex
The price is AU$62
includes taxes & fees
18 Jan - 19 Jan 2026
Capital O Colón, Ciudad Guzmán Jalisco

La Casa de los Patios Hotel & Spa

La Casa de los Patios Hotel & Spa
3.5 star property
Sayula
9.4 out of 10, Exceptional, (144)
"The hotel is beautiful and staffing is great!"
United States
Tony
La Casa de los Patios Hotel & Spa

Tryp By Wyndham Ciudad Guzman Uttsa

Tryp By Wyndham Ciudad Guzman Uttsa
3.0 star property
Zapotlán el Grande
9.6 out of 10, Exceptional, (79)
"Excelente "
Mexico
Adrian Quirino
The price is AU$100
includes taxes & fees
25 Dec - 26 Dec
Tryp By Wyndham Ciudad Guzman Uttsa

Hotel Zapotlan

Hotel Zapotlan
2.5 star property
Zapotlán el Grande
8.0 out of 10, Very good, (237)
"Rooms are ok"
United States
Noe
The price is AU$64
includes taxes & fees
25 Dec - 26 Dec
Hotel Zapotlan

Gran Casa Sayula Hotel & Spa

Gran Casa Sayula Hotel & Spa
4.0 star property
Sayula
9.4 out of 10, Exceptional, (125)
"Great hotel in Sayula!!"
United States
Joseph
Gran Casa Sayula Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in La Mesa?
Based on our traveller data, Chalet de Colombo Hotel is one of the top choices for your stay. This ranch offers free parking and free WiFi. Two other options for your stay in the area are Tryp By Wyndham Ciudad Guzman Uttsa and Hotel Zapotlan. See all available top hotels, or vacation rentals in La Mesa.
What are some of the best holiday rentals that La Mesa has to offer?
Finca El Campanario: This holiday home rental outside of La Mesa offers a garden and a BBQ to help you feel comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a fridge, an oven and a microwave, so that you can cook with friends or family. See all vacation rentals in La Mesa.
If I need to cancel my hotel reservation in La Mesa, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.
What's it like staying in La Mesa?
Travellers to La Mesa will find plenty to explore and enjoy. There are 27 hotels and other accommodation options in the surrounding area. Find out more about La Mesa.
What is there to see in La Mesa?
Places to visit in the wider area include Laguna de Ciudad Guzman, Volcan Nevado de Colima National Park and Volcano of Colima. You'll also find Las Penas Ecological Park and Nevado de Colima Trailhead in the area. Take a look at what more there is to see and do in Expedia's La Mesa guide.
What's the weather like in La Mesa?
The hottest months are usually May and April, with an average temperature of 21°C, while the coldest months are January and February, with an average of 17°C. The rainiest months in La Mesa are August, July, September and June, with each month seeing an average of 360 mm of rainfall.

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