La Mesa Holiday Rentals

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Holiday Rentals in La Mesa

Arcadia Condo Suites

2.5 star property
9.2 out of 10, Wonderful, (69)
"Comfortable & good location"
The price is AU$159
includes taxes & fees
11 Sept - 12 Sept
Arcadia Condo Suites

San Francisco by Wynwood House

3.0 star property
9.4 out of 10, Exceptional, (47)
"Good comfy rooms"
The price is AU$200
includes taxes & fees
17 Sept - 18 Sept
San Francisco by Wynwood House

Boutique Apartments Panamá Coco del Mar

3.5 star property
7.6 out of 10, Good, (129)
"Great view with access to the pool and gym."
The price is AU$254
includes taxes & fees
17 Sept - 18 Sept
Boutique Apartments Panamá Coco del Mar

Boutique Apartments Atlapa

3.0 star property
7.2 out of 10, Good, (19)
"Buen lugar para estar por unos días en Panamá"
Boutique Apartments Atlapa

Delightful Ocean View

3.5 star property
10.0 out of 10, Exceptional, (1)
"Muy buena ubicación. Apartamento moderno, con buena vista. Único defecto para resaltar era la máquina lavadora de ropa, que estaba en mal estado."
Delightful Ocean View

Lodging cerro viento, 2 bedroom apartment with air conditioning.

10.0 out of 10, Exceptional, (1)
"Tiene todo lo necesario en perfectas condiciones."
Lodging cerro viento, 2 bedroom apartment with air conditioning.

Ocean-view Luxe 2-Bedroom at Magnificent Wanders Yoo, Ave Balboa, Panama City!

8.0 out of 10, Very good, (3)
"Beautiful amenities and excellent location"
Ocean-view Luxe 2-Bedroom at Magnificent Wanders Yoo, Ave Balboa, Panama City!

Hidden Gem Home in the Heart of Panama

Hidden Gem Home in the Heart of Panama

Blue Dream in San Francisco

2.0 star property
Blue Dream in San Francisco

Three-bedroom apartment with ocean views, pool, gym C20C

10.0 out of 10, Exceptional, (1)
"We loved the location, the apartment was spacious, very modern, clean, has security. The view was amazing specially at night. Walking distance to restaurants. We enjoyed our visit, definitely recommend it."
The price is AU$398
includes taxes & fees
15 Sept - 16 Sept
Three-bedroom apartment with ocean views, pool, gym C20C

w* | Prestigious 1BR in San Francisco

10.0 out of 10, Exceptional, (1)
"Everything was as described. Restaurants were conveniently located. View was an added bonus and was better than pictured. We were able to enjoy the gym. The pool was a little cool but still enjoyable. Would recommend this host."
The price is AU$191
includes taxes & fees
14 Sept - 15 Sept
w* | Prestigious 1BR in San Francisco

w Bright 1BR w Private Balcony in San Francisco

2.0 star property
The price is AU$209
includes taxes & fees
15 Sept - 16 Sept
w Bright 1BR w Private Balcony in San Francisco

Luxury 3 Bedroom Oceanview apt w parking balcony

8.0 out of 10, Very good, (2)
"We enjoyed our stay at the condo. The accommodations were within walking distance to some restaurants. Our favorite for Panamanian cuisine was Brazas. There was also fast food (McDonald’s and Carl’s Jr.). Two supermarkets were within walking distance, Super 99 (5 min walk), El Rey (10 min walk). In addition there were more restaurants to choose from within a 10 min drive. The area was safe and quiet. The view from the condo is exactly as described with a nice ocean view. The security and host...
The price is AU$291
includes taxes & fees
14 Sept - 15 Sept
Luxury 3 Bedroom Oceanview apt w parking balcony

w* | Exciting 1BR in San Francisco

10.0 out of 10, Exceptional, (1)
"Very comfortable small apartment with all you need!"
The price is AU$191
includes taxes & fees
11 Sept - 12 Sept
w* | Exciting 1BR in San Francisco

Modern Apartment in a Luxurious Residential Unit in the heart of the city

9.6 out of 10, Exceptional, (4)
"I always wanted to return to Panama for vacation. Doris provided excellent accommodations for the time spent in the city. The apartment was in a good location and was very clean. I would highly recommend this property."
Modern Apartment in a Luxurious Residential Unit in the heart of the city

Apartment in San Francisco

2.0 star property
8.0 out of 10, Very good, (1)
"Nice place with 3 TV's, secure parking. Owner allowed us to drop our luggage off while they cleaned it from previous guests. Many restaurants nearby including new Burger King, Popeye's and McDonalds. Plus Vietnamese, Panamanian, a bakery, etc. Not that close to water or subway tho."
The price is AU$179
includes taxes & fees
14 Sept - 15 Sept
Apartment in San Francisco

Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá

10.0 out of 10, Exceptional, (1)
"The address was a bit confusing for the taxi drivers; they should mention that it is within the “Villas de Cantabria” gated area. You’ll have to call to be let in through the gate upon first arrival. Other than that, great place. It’s close to a train station and a supermarket."
Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá

Blue Dream in San Francisco

10.0 out of 10, Exceptional, (3)
"Property was as described, A/C in every room, very clean, full kitchen so we could eat in as near a grocery store and bakery, Alberto quickly responded to questions, would highly recommend. Safe neighborhood was important. Thanks, Alberto!"
The price is AU$173
includes taxes & fees
14 Sept - 15 Sept
Blue Dream in San Francisco

Spectacular apartment

The price is AU$155
includes taxes & fees
11 Sept - 12 Sept
Spectacular apartment

Apartamento a 10 minutos Aeropuerto Internacional de Tocumen #2 Panamá

The price is AU$106
includes taxes & fees
14 Sept - 15 Sept
Apartamento a 10 minutos Aeropuerto Internacional de Tocumen #2 Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top La Mesa Hotel Reviews

Find out more about La Mesa

Find out more about La Mesa

Everything you need to know about La Mesa holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the La Mesa holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Mesa holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

La Mesa holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in La Mesa. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A La Mesa holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of La Mesa holiday rentals we have selected for you start as low as AU$106 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on La Mesa rentals

At Expedia, we put the best La Mesa holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top La Mesa rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Mesa holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Mesa. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals close to the most popular sights in La Mesa, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that La Mesa has to offer?

LILIA HOUSE 10 MINUTES AIRPORT: This holiday home rental outside of La Mesa has air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities such as a stovetop and a microwave can make your holiday run smoothly.

What’s there to see and do in La Mesa?

While exploring the area, visit family-friendly sights like Chepo Youth Recreation Center, or get outside and enjoy nature at Chagres National Park. In the wider area, you’ll find Metromall Panama and Los Pueblos Commercial Center.

What’s a holiday rental in La Mesa like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in La Mesa. Holiday rentals provide amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you to travel. You'll also find more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a great option for families.