Uptown - Upper Duval Travel Guide
Tourist Guide
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim.
Key West Butterfly and Nature Conservatory
Encounter hundreds of butterflies in a tropical rainforest setting, butterfly-friendly birds and an indoor waterfall at this popular Key West attraction.
Activities
Historic Key West Old Town Trolley Hop-On Hop-Off Tour
Key West Coral Reef Snorkel with Mimosas, Margaritas or Rum Punch
Key West Half-Day Fishing Charter
Schooner Appledore Day Sail with Full Bar in Key West
Key West Afternoon At The Reef Snorkeling Adventure with Open Bar!
Our pick of the best Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
Staff and amenities
Reviewed on 8 Jan 2026
The Reach Key West, Curio Collection by Hilton
Excellent location on the water. Friendly and courteous staff. Pet friendly. They had the option to secure my luggage for a few hrs because my flight was much later in the evening. I could see the sunrise from my balcony. ❤️ Loved the whole experience. Hope to return for another vacation soon !! ...
Reviewed on 4 Jan 2026
The Southernmost Inn - Adults Only
Property was good, great location. Room could have been cleaned better. Bed was very uncomfortable.
Reviewed on 8 Jan 2026
Southwinds Motel
Check-in staff was kind and friendly. We arrived at the hotel earlier and they accommodated an early check in as there was a room ready.
Reviewed on 8 Jan 2026
Douglas House
Room was outfitted with everything one could ask for. Location was perfect for a stay on Key West! Staff was incredibly helpful ! Can’t say enough positive things during our stay.
Reviewed on 9 Jan 2026
Southernmost House
What a gorgeous property, the mansion is gorgeous and the views were awesome. It was so nice to walk out of the property and enjoy all that Duvall street has to offer without ever needing our car.
Reviewed on 29 Dec 2025
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Other neighbourhoods around Uptown - Upper Duval
Old Town Key West
While visiting Old Town Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.
Bahama Village
Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.
Key West Historic District
Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Key West Cemetery.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
White Street Gallery District
If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Duval Street and Clarence S. Higgs Memorial Beach Park.
