
Isolotto Holidays
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Your Isolotto Holiday
Reserving a tailor-made Isolotto holiday package is a good way to know the ins and outs of this unique neighbourhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next holiday to Isolotto, Expedia is here to help.
Our guide on where to stay in Isolotto

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Our pick of the best Isolotto Hotel Deals

IQ Hotel Firenze
The staff was very nice willing to assist us in every request. The hotel was excellent with premium amenities. The room was amazing spacious and with a very modern decoration. The bathroom was spacious and isolated!!!! Recommend 100%
Reviewed on 30 Dec 2025

25hours Hotel Florence Piazza San Paolino
Very detailed decor and very clean!
Reviewed on 5 Jan 2026

Solo Experience Hotel
Room was ok. Nice bed and clean room
Reviewed on 9 Jan 2026
Frequently asked questions
Discover the most popular places to visit in Isolotto

Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the acclaimed art galleries in this vibrant area.

Cathedral of Santa Maria del Fiore
The magnificent dome of Santa Maria del Fiore provides the Florentine skyline with one of its most iconic outlines.

Ponte Vecchio
The shop-lined Ponte Vecchio over the River Arno is one of Florence’s most familiar and most romantic landmarks.
Activities

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
















