A calm lake with a small boat, a dock with colorful buildings, and a forested hill in the background.

Luxury Hotels & Resorts in Isla Grande from AU$54

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Isla Grande Luxury Hotels

Tonight
29 Sept - 30 Sept
Tomorrow
30 Sept - 1 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Isla Grande luxury hotels

A bedroom with a bed, a TV, and a balcony with a view of the sea.
A spa area with two massage tables, a wooden deck, and a view of the ocean.
A bathtub with water, towels, and flowers on a balcony overlooking the sea.
A beach resort with a pier, umbrellas, and a small island in the background.

1. Ordovician Beach Resort

Ordovician Beach Resort
Isla Grande
  • Private beach luxury with full-service spa treatments and beachfront massages awaits at this island retreat in Isla Grande.
AU$685
includes taxes & fees
12 Oct - 13 Oct
Ordovician Beach Resort
View all properties

Top Isla Grande Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in Isla Grande?
Expedia can help you get a flight to Panama City (PTY-Tocumen Intl.) airport or Panama City (PAC-Marcos A. Gelabert Intl.) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a holiday, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Isla Grande has to offer.
What's the best high-end place to stay in Isla Grande?
Ordovician Beach Resort is a luxury resort with a private beach and 2 restaurants, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in Isla Grande?
Planning for the weather is a good way to make your trip to Isla Grande relaxing and enjoyable, especially when you're splurging. The hottest months are usually May and September, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Isla Grande are November, July, August and October, with each month seeing an average of 350 mm of rainfall.
What's there to see and do in Isla Grande?
When you're in Isla Grande, enjoy exploring the sights and attractions here including Isla Mamey, Blanca Beach and Playa La Angosta. If you have a little extra time during your trip, you might want to check out Portobelo National Park and San Felipe Church.

Explore a world of travel with Expedia