Puerto Santa Ana Hotels, Guayaquil

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Puerto Santa Ana hotels

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Airport transfer and breakfast were great!"
United States
Halima
The price is AU$152
14 June - 15 June
Wyndham Guayaquil Puerto Santa Ana

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
8.8 out of 10, Excellent, (54 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is AU$112
22 June - 23 June
River View suites Puerto Santa Ana gye

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
9.7 km from Puerto Santa Ana
2.0 out of 10, (1 review)
"Deben haber un mejor desayuno, al menos frutas. No es tan bueno como parecía"
United States
Damariz
The price is AU$68
9 June - 10 June
NP Hotel & Suites

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
5.4 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (48 reviews)
"Breakfasts were excellent. Staff went out of their way to accommodate late arrival. "
Canada
Kimberly
The price is AU$161
22 June - 23 June
Iguanazu Bed & Breakfast

Hotel del Parque

Hotel del Parque
4.5 star property
3.6 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (115 reviews)
"Breakfast excellent"
United States
Priscilla
The price is AU$448
11 June - 12 June
Hotel del Parque

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,009 reviews)
"Great place"
Canada
Michael
The price is AU$160
21 June - 22 June
Holiday Inn Guayaquil Airport by IHG

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (98 reviews)
"Nice business hotel for staying when working abroad"
United States
wagner
The price is AU$109
4 July - 5 July
Doubletree By Hilton Guayaquil

Casa con Piscina Privada para Familias

Casa con Piscina Privada para Familias
3.0 star property
15.7 km from Puerto Santa Ana
2.0 out of 10, (2 reviews)
"More cleaning, there was rotten garbage and a bad smell emanated"
United States
Isabel
The price is AU$193
9 June - 10 June
Casa con Piscina Privada para Familias

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 3.2 km from Puerto Santa Ana
8.6 out of 10, Excellent, (921 reviews)
"Excellent stay highly recommended"
United States
Carol
The price is AU$170
30 June - 1 July
Hilton Colon Guayaquil

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
3.3 km from Puerto Santa Ana
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is AU$68
9 June - 10 June
Hotel La Ria Durán

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 2.9 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (655 reviews)
"The food was delicious the staff was very friendly I recommend this hotel "
Canada
Monica
The price is AU$183
12 June - 13 June
Sheraton Guayaquil Hotel

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,014 reviews)
"Great place to stay"
United States
Daniel
The price is AU$136
12 June - 13 June
Oro Verde Guayaquil

MundialCity Hotel Guayaquil

MundialCity Hotel Guayaquil
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
8.4 out of 10, Very good, (172 reviews)
"We stay here anytime that we have a late arrival or early flight from Ecuador. They are always helpful when we are looking for something. There is a traditional Ecuadorian family type restaurant 100 feet from the hotel and several rental car agencies a couple of hundred meters from there. And naturally my daughter loves the pool. "
United States
Christopher
The price is AU$68
9 June - 10 June
MundialCity Hotel Guayaquil

NCG Suite 5

NCG Suite 5
2.5 star property
7.1 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"loved everything "
United States
Betty
The price is AU$50
15 June - 16 June
NCG Suite 5

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 3.5 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (181 reviews)
"Love the breakfast menu and security."
United States
Marcela
The price is AU$138
9 June - 10 June
Luxva Hotel Boutique

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (139 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is AU$94
10 June - 11 June
Mansión del Río

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is AU$661
30 June - 1 July
Hotel Río Guayas by Art Hotels Ecuador

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (10 reviews)
"Very convenient to airport and local shopping. Outstanding service and price."
United States
Scottie
The price is AU$101
9 June - 10 June
Hostal Macaw

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,005 reviews)
"Nice place, close to everything"
United States
Amira
The price is AU$127
12 June - 13 June
Wyndham Garden Guayaquil

Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (694 reviews)
"Good hotel"
United States
juan pablo
The price is AU$142
14 June - 15 June
Radisson Hotel Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and La Rotonda while you're in town.

Bolívar

While Bolívar may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Malecon Mall and Sports Federation of Guayas.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Top Puerto Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 80 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.

Explore a world of travel with Expedia