
Epipoli Holidays
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Your Epipoli Holiday
Reserving a tailor-made Epipoli holiday package is a wonderful way to become familiar with this neighbourhood. From its must-see spots to its lesser-known delights, you won't be short of new adventures. When it's time to get out and explore, you'll find a lot of popular attractions nearby including Cathedral of Syracuse, Temple of Apollo and Castello Eurialo. Visit one, two or more during your trip to Epipoli. Expedia will help you turn your ideal Epipoli holiday into reality, no matter your budget or travel plans.
Our guide on where to stay in Epipoli

Ortigia
Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.
Our pick of the best Epipoli Hotel Deals

Algila' Ortigia Charme Hotel
Fantastic hotel! Large, lovely room in beautiful, completely renovated 19th century building that is steps from the waterfront. Terrific breakfast, very friendly, helpful staff. Highly recommend!
Reviewed on 6 Jan 2026

Grand Hotel Ortigia Siracusa
Stunning hotel and area on the waterfront in Ortigia. Strongly recommend everything except the restaurant. Food was marginal for the price with much better options close by
Reviewed on 31 Dec 2025

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Great hotel and saff
Reviewed on 20 Oct 2025
Frequently asked questions
Discover the most popular places to visit in Epipoli

Roman Amphitheatre of Syracuse
You can learn about the history of Syracuse with a trip to Roman Amphitheatre of Syracuse. Wander the seaside in this culturally rich area.
Museo Archeologico Regionale Paolo Orsi
You can study the exhibits at Museo Archeologico Regionale Paolo Orsi, a museum with a story of its own, during your trip to Syracuse. Wander the seaside in this culturally rich area.
Activities

Syracuse: Boat Tour of Ortigia Island and Sea Caves

Tour of the island of Ortigia and exploration of sea caves with baths.













