Business Hotels & Resorts in Eastern Sicily from AU$108

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Check prices for these dates

Tonight
8 Nov - 9 Nov
Tomorrow
9 Nov - 10 Nov
Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

Our top choices for Eastern Sicily business-friendly hotels

A stone pathway leading to a sunset view, flanked by lanterns and greenery.

1. Borgo Pantano

Borgo Pantano
4.0 star property
Syracuse
9.8 out of 10, Exceptional, (286 reviews)
"Gorgeous place to relax with two swimming pools in the quiet environment. Great breakfast and dinner. Appreciate the hospitality."
United States
Yan
The price is AU$249
includes taxes & fees
10 Nov - 11 Nov
Borgo Pantano
A poolside setting with a person relaxing, a table with a drink and fruit, and a view of the pool and chairs in the background.

2. Hotel Parco delle Fontane

Hotel Parco delle Fontane
4.0 star property
Tiche
9.2 out of 10, Wonderful, (315 reviews)
"Great staff very clean great food beautiful pool we loved it ♥️"
United States
Tony
The price is AU$168
includes taxes & fees
9 Nov - 10 Nov
Hotel Parco delle Fontane
A modern lobby with a blue armchair, a beige sofa, and a coffee table with magazines. There are potted plants and a large window with natural light.

3. Modica Boutique Hotel

Modica Boutique Hotel
4.0 star property
Modica
9.0 out of 10, Wonderful, (67 reviews)
"Clean room, lovely property"
United Kingdom
Joanne
The price is AU$147
includes taxes & fees
8 Dec - 9 Dec
Modica Boutique Hotel
A bakery display with various baked goods and a sign indicating apple and jam cake.

4. UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA
4.0 star property
Grottasanta
8.6 out of 10, Excellent, (555 reviews)
"Breakfast excellent, with hot breakfast cooked to order. Staff are very friendly. Executive room was very clean."
United Kingdom
Michelle
The price is AU$174
includes taxes & fees
9 Nov - 10 Nov
UNA Hotels One Siracusa Wellness & SPA
A poolside area with lounge chairs and a table, overlooking a beach and the sea.

5. Albergo Terrazze Sul Mare

Albergo Terrazze Sul Mare
3.0 star property
Pozzallo
9.0 out of 10, Wonderful, (176 reviews)
"Fantastic location, walking distance to train, bus and ferry. Lovely location close to beach and yummy breakfast."
Australia
SUSAN
The price is AU$108
includes taxes & fees
14 Nov - 15 Nov
Albergo Terrazze Sul Mare
A courtyard with stone buildings, potted plants, and a gravel pathway.

6. San Giorgio Palace Hotel

San Giorgio Palace Hotel
4.0 star property
Ragusa Ibla
9.4 out of 10, Exceptional, (617 reviews)
"Short stay. Clean, comfortable and nice breakfast. Easy parking on the roadside too."
United Kingdom
Gregg
The price is AU$158
includes taxes & fees
8 Dec - 9 Dec
San Giorgio Palace Hotel
A hot tub with a view of the sea, wicker chairs, and a table with drinks and flowers.

7. Maniace Boutique Hotel Ortigia UNA Esperienze

Maniace Boutique Hotel Ortigia UNA Esperienze
Ortigia
10.0 out of 10, Exceptional, (115 reviews)
"Very nice property, well maintained, rooms was clean, staff is very coporative, enjoyed our stay"
United States
Asha
The price is AU$364
includes taxes & fees
1 Dec - 2 Dec
Maniace Boutique Hotel Ortigia UNA Esperienze
A balcony with a hot tub, lounge chairs, and a view of the sea.

8. Nautilus Hotel

Nautilus Hotel
4.0 star property
Giardini Naxos
9.4 out of 10, Exceptional, (252 reviews)
"Great property and friendly staff."
United States
David
The price is AU$156
includes taxes & fees
1 Dec - 2 Dec
Nautilus Hotel
A woman holding a wine glass on a balcony overlooking a street with historic buildings and a clock tower.

9. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
4.0 star property
Ortigia
9.4 out of 10, Exceptional, (696 reviews)
"Overall a windy experience. Perfect location in Ortigia / Syracusa."
United States
Joanne
The price is AU$251
includes taxes & fees
9 Dec - 10 Dec
Palazzo Artemide - VRetreats, SLH Collection
A coastal terrace with wicker furniture, striped umbrellas, and a rocky backdrop.

10. Grand Hotel Villa Politi

Grand Hotel Villa Politi
4.0 star property
Grottasanta
8.6 out of 10, Excellent, (987 reviews)
"lovely hotel beautiful quiet pool breakfast was plentiful with lots of choice"
United Kingdom
Michelle
The price is AU$181
includes taxes & fees
9 Dec - 10 Dec
Grand Hotel Villa Politi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Eastern Sicily Hotel Reviews

A hot tub with a view of the sea, wicker chairs, and a table with drinks and flowers.
Maniace Boutique Hotel Ortigia UNA Esperienze

Maniace Boutique Hotel Ortigia UNA Esperienze

Maniace Boutique Hotel Ortigia UNA Esperienze
Ortigia

10/10 Excellent

My time at Maniace Boutique Hotel was so much more than a stay… it was a truly wonderful experience from beginning to end. From the outset, communication was exceptionally professional, including the seamless arrangement of my airport transfer on arrival. I was greeted so warmly by Luca, and throughout my five day stay, every member of staff made me feel incredibly special. They consistently went above and beyond to ensure I had a wonderful experience. Luca, Massimo, Lorenzo and the entire staff...
Australia
Justine
Reviewed July 28, 2026
Maniace Boutique Hotel Ortigia UNA Esperienze

Frequently Asked Questions

How much do business-friendly hotels in Eastern Sicily cost?

Business-friendly hotels in Eastern Sicily range between AU$108 and AU$363 per night. This means you can lock in a stay with welcome amenities like workspaces and conference rooms at a price that's easy on your wallet. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

How many business-friendly hotels are there in Eastern Sicily?

Take your pick of 1,674 business-friendly hotels in Eastern Sicily. When work takes you on the road, Expedia can help you find the perfect space with the amenities you want.

What is there to do in Eastern Sicily near my business-friendly hotel?

Whether you're passionate about arts, culture, shopping or dining, Eastern Sicily promises something for everyone! The well-known city of Catania has plenty of sights and experiences, including Ursino Castle, Catania Cathedral and Catania Beach. If you're arranging a business trip to Syracuse, Cathedral of Syracuse, Greek Theatre of Syracuse and Ear of Dionysius shouldn't be missed.