
Eastern Panama Holidays
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Your Eastern Panama Holiday
Leave all the planning to us with an Eastern Panama holiday package. With everything organised before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama holiday into reality.
Eastern Panama Holiday
Eastern Panama Essential Information
Language | Spanish |
---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Tocumen Intl. Airport (PTY) |
Top Sights | Portobelo National Park, Isla Mamey and Cayos Holandeses |
Our pick of the best Eastern Panama Hotel Deals

Ordovician Beach Resort
Isla Grande, Isla Grande, Colon
The price is AU$924 per night from 13 May to 14 May
AU$924
includes taxes & fees
13 May - 14 May

Ciel y Miel
Caillle Principale, Cacique, Provincia de Colón
The price is AU$393 per night from 3 May to 4 May
AU$393
includes taxes & fees
3 May - 4 May
10/10 Exceptional! (4 reviews)
"Is an execelent place to relax, enjoy nice food and view. It has access to a beautiful beach which is not overcrowded and the staff is on top of everything. Me and my family are definetly coming back!!!"
Reviewed on 3 Mar. 2025

Private Over the Water Cabin on San Blas Island
9.542876, -78.899058, Narganá, San Blas
The price is AU$358 per night from 1 May to 2 May
AU$358
includes taxes & fees
1 May - 2 May
6.4/10 (5 reviews)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were ..."
Reviewed on 16 Feb. 2022
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
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Flights
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.