Business Hotels & Resorts in Downtown Buffalo from AU$227
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Downtown Buffalo Business Hotels
Tonight
Tomorrow
This weekend
Next weekend
Our top choices for Downtown Buffalo business-friendly hotels
1. Hyatt Regency Buffalo / Hotel and Conference Center
Hyatt Regency Buffalo / Hotel and Conference CenterDowntown Buffalo
8.2 out of 10, Very good, (1,832 reviews)
The price is AU$227
includes taxes & fees
17 Oct - 18 Oct
9.0 out of 10, Wonderful, (1,896 reviews)
"Great staff, clean rooms, nice breakfast."
Amir
The price is AU$259
includes taxes & fees
12 Oct - 13 Oct
8.6 out of 10, Excellent, (1,004 reviews)
"Excellent location. Excellent room and service."
Mercedes
The price is AU$257
includes taxes & fees
11 Oct - 12 Oct
8.4 out of 10, Very good, (1,001 reviews)
"This is one of most clean hotel I have seen. Also the location is downtown with good views. The Staff was amazing."
DIPELE
The price is AU$284
includes taxes & fees
18 Oct - 19 Oct
5. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHGDowntown Buffalo
8.4 out of 10, Very good, (1,010 reviews)
"Front desk staff were very helpful."
Robert
The price is AU$272
includes taxes & fees
29 Sept - 30 Sept
9.0 out of 10, Wonderful, (1,002 reviews)
"Amazing location and incredible staff!!"
Diana
The price is AU$379
includes taxes & fees
18 Oct - 19 Oct
9.4 out of 10, Exceptional, (1,004 reviews)
"Great place to stay!"
Marilyn
The price is AU$296
includes taxes & fees
4 Oct - 5 Oct
9.2 out of 10, Wonderful, (434 reviews)
"Nice brunch"
Sarah
The price is AU$393
includes taxes & fees
18 Oct - 19 Oct
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Downtown Buffalo Hotel Reviews
Buffalo Airport Hotel
10/10 Excellent
Explore a world of travel with Expedia
- Hotels near American Falls
- All Inclusive Hotels in Buffalo
- Comfort Inn & Suites Hamburg
- Lgbt Welcoming Hotels in Buffalo
- Buffalo Hotels
- Clarence Hotels
- Elma Center Hotels
- Elmwood Village Hotels
- Hamburg Hotels
- Pet Friendly Hotels in Jamestown
- Cheap Hotels in Java Center
- Lancaster Hotels
- Holiday Inn Niagara Falls State Park Entry by IHG
- This Old House
- Niagara Falls Hotels
- B&B in North Tonawanda
- Orchard Park Motel
- Flights to Buffalo
- Flights to Niagara Falls
- Flights from Buffalo Niagara Intl.
- Flights from Niagara Falls Intl.
- Flights from Buffalo
- Flights from Niagara Falls
- Flights from Adelaide (ADL) to Buffalo (BUF)
- Flights from Adelaide (ADL) to Niagara Falls (IAG)
- Flights from Augusta (AGS) to Niagara Falls (IAG)
- Flights from Atlanta (ATL) to Buffalo (BUF)
- Flights from Brisbane (BNE) to Buffalo (BUF)
- Flights from Boston (BOS) to Buffalo (BUF)
- Flights from Boston (BOS) to Niagara Falls (IAG)
- Flights from Buffalo (BUF) to Niagara Falls (IAG)
- Flights from Canberra (CBR) to Buffalo (BUF)
- Flights from Charleston (CHS) to Buffalo (BUF)
- Flights from Washington (DCA) to Buffalo (BUF)
- Flights from Washington (DCA) to Niagara Falls (IAG)
- Flights from Denver (DEN) to Buffalo (BUF)
- Flights from Detroit (DTW) to Buffalo (BUF)
- Flights from Newark Liberty Intl. Airport (EWR) to Buffalo (BUF)
- Flights from Newark Liberty Intl. Airport (EWR) to Niagara Falls (IAG)
- Flights from Fort Lauderdale (FLL) to Buffalo (BUF)
- Flights from Fort Lauderdale (FLL) to Niagara Falls (IAG)
- Flights from New York (JFK) to Buffalo (BUF)
- Flights from New York (JFK) to Niagara Falls (IAG)
- Flights from Las Vegas (LAS) to Buffalo (BUF)
- Flights from Los Angeles (LAX) to Buffalo (BUF)
- Flights from Los Angeles (LAX) to Niagara Falls (IAG)
- Flights from New York (LGA) to Buffalo (BUF)
- Flights from Melbourne (MEL) to Buffalo (BUF)
- Flights from Melbourne (MEL) to Niagara Falls (IAG)
- Flights from Memphis (MEM) to Buffalo (BUF)
- Flights from Miami (MIA) to Buffalo (BUF)
- Flights from Miami (MIA) to Niagara Falls (IAG)
- Flights from Melbourne (MLB) to Buffalo (BUF)
- Flights from Minneapolis (MSP) to Buffalo (BUF)
- Flights from New Orleans (MSY) to Buffalo (BUF)
- Flights from New York (NYC) to Buffalo (BUF)
- Flights from New York (NYC) to Niagara Falls (IAG)
- Flights from Chicago (ORD) to Buffalo (BUF)
- Flights from Chicago (ORD) to Niagara Falls (IAG)
- Flights from Perth (PER) to Buffalo (BUF)
- Flights from Perth (PER) to Niagara Falls (IAG)
- Flights from Philadelphia (PHL) to Buffalo (BUF)
- Flights from Philadelphia (PHL) to Niagara Falls (IAG)
- Flights from Portland (PWM) to Niagara Falls (IAG)
- Flights from Seattle (SEA) to Buffalo (BUF)
- Flights from Seattle (SEA) to Niagara Falls (IAG)
- Flights from San Francisco (SFO) to Buffalo (BUF)
- Flights from Sydney (SYD) to Buffalo (BUF)
- Flights from Sydney (SYD) to Niagara Falls (IAG)
- Flights from Knoxville (TYS) to Niagara Falls (IAG)
- Flights from West Yellowstone (WYS) to Niagara Falls (IAG)
- Flights from Banff (YBA) to Niagara Falls (IAG)
- Flights from Ottawa (YOW) to Buffalo (BUF)
- Flights from Montreal (YUL) to Buffalo (BUF)
- Flights from Montreal (YUL) to Niagara Falls (IAG)
- Flights from Vancouver (YVR) to Buffalo (BUF)
- Flights from Vancouver (YVR) to Niagara Falls (IAG)
- Flights from Winnipeg (YWG) to Niagara Falls (IAG)
- Flights from Calgary (YYC) to Buffalo (BUF)
- Flights from St. John's (YYT) to Niagara Falls (IAG)
- Flights from Toronto (YYZ) to Buffalo (BUF)