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24 Dec - 25 Dec
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25 Dec - 26 Dec
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26 Dec - 28 Dec
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Our top choices for Perry County hotels

Exterior
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (543)
"lean, updated rooms, friendly staff and great breakfast."
United States
Linda
The price is AU$149
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express & Suites Perryville by IHG
Suite, 1 King Bed, Non Smoking (1 Bedroom)
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very good, (942)
"My girlfriend found hair and leaves in the tub of our room. This is after we checked in and it was only for one night."
United States
Timothy
The price is AU$112
includes taxes & fees
31 Dec - 1 Jan 2026
Super 8 by Wyndham Perryville
Lobby
Quality Inn Perryville I-55

Quality Inn Perryville I-55

Quality Inn Perryville I-55
2.5 star property
Perryville
6.6 out of 10, (124)
"Nice place would recommend Mary Jane’s if you’re looking for good food "
United States
Andrew
The price is AU$118
includes taxes & fees
31 Dec - 1 Jan 2026
Quality Inn Perryville I-55
Room, 1 King Bed | Jetted bathtub
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
2.0 star property
Perryville
6.8 out of 10, (415)
"Was a nice place."
United States
Lesliee
The price is AU$106
includes taxes & fees
25 Jan - 26 Jan 2026
Days Inn by Wyndham Perryville
Outdoor spa tub
Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin
Perryville
9.8 out of 10, Exceptional, (8)
"Property was excellent house was really nice and in a great location would stay there again for sure "
United States
David R.
Hot Tub & Creek Views: Secluded Perryville Cabin
Exterior
The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (32)
"Hosts were great. I just wish they had a second bath or atleast a larger bathroom. "
United States
Dennis H.
The price is AU$251
includes taxes & fees
1 Jan - 2 Jan 2026
The Weber Farm - Enjoy a beautiful 100 acre farm!
Property grounds
TreeLoft at BaseCamp

TreeLoft at BaseCamp

TreeLoft at BaseCamp
2.0 star property
Perryville
10.0 out of 10, Exceptional, (5)
"This place is perfect if you want a private upscale experience that is immersed in natural beauty. The treehouse is luxurious and so comfortable. We loved every minute of our stay. "
United States
joel r.
TreeLoft at BaseCamp
Interior
Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant

Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant

Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant
Perryville
10.0 out of 10, Exceptional, (1)
"Everything was perfect!"
United States
Thor L.
The price is AU$478
includes taxes & fees
28 Dec - 29 Dec
Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant
Private kitchen
Gorgeous, downtown house!

Gorgeous, downtown house!

Gorgeous, downtown house!
Perryville
10.0 out of 10, Exceptional, (1)
"Our stay was excellent and our host Carisa was a Great person to work with. The house was beautiful. The house worked out great for us. We had 6 people staying and we all had very comfortable beds and our own bathrooms. Great for a large family. "
United States
Doyle or Cheryl D.
The price is AU$1,320
includes taxes & fees
30 Dec - 31 Dec
Gorgeous, downtown house!
House (Multiple Bedrooms) | Interior
Missouri Castle w/ Private Lake, Pool & 100 Acres!

Missouri Castle w/ Private Lake, Pool & 100 Acres!

Missouri Castle w/ Private Lake, Pool & 100 Acres!
3.0 star property
St Mary
Missouri Castle w/ Private Lake, Pool & 100 Acres!
Dining
Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops.

Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops.

Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops.
Saint Mary
9.8 out of 10, Exceptional, (7)
"Large space which was great. Big bedrooms. "
United States
Robin
Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops.
Full-sized fridge, microwave, oven, stovetop
Urban Lofts

Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
United States
Eric
Urban Lofts
House (3 Bedrooms) | Interior
Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin
3.0 star property
Perryville
Hot Tub & Creek Views: Secluded Perryville Cabin
Fridge, microwave, oven, stovetop
Downtown Loft w/ Amazing Bath Tub & Shower

Downtown Loft w/ Amazing Bath Tub & Shower

Downtown Loft w/ Amazing Bath Tub & Shower
Perryville
10.0 out of 10, Exceptional, (6)
"Amazing place. "
United States
Brandy P.
Downtown Loft w/ Amazing Bath Tub & Shower
Private kitchen
Historic House in heart of Altenburg

Historic House in heart of Altenburg

Historic House in heart of Altenburg
2.0 star property
Altenburg
10.0 out of 10, Exceptional, (1)
"Great place to stay Quite and clean"
United States
Catherine M.
Historic House in heart of Altenburg
Microwave, oven, stovetop, dishwasher
Tranquil and relaxing living quarters surrounded by nature.

Tranquil and relaxing living quarters surrounded by nature.

Tranquil and relaxing living quarters surrounded by nature.
2.0 star property
Frohna
Tranquil and relaxing living quarters surrounded by nature.
House (0 Bedroom) | Interior
'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!

'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!

'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!
3.0 star property
Perryville
10.0 out of 10, Exceptional, (2)
"The house and host were just awesome, enjoyed our stay Toni even helped me Extend!! Would def stay again:)"
United States
Shandese
'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!
Interior
Urban Loft #8 METALL · Downtown Urban Loft above Restaurants & Boutiques

Urban Loft #8 METALL · Downtown Urban Loft above Restaurants & Boutiques

Urban Loft #8 METALL · Downtown Urban Loft above Restaurants & Boutiques
2.0 star property
Perryville
The price is AU$320
includes taxes & fees
26 Dec - 27 Dec
Urban Loft #8 METALL · Downtown Urban Loft above Restaurants & Boutiques
TV
Downtown Urban Loft above Restaurants

Downtown Urban Loft above Restaurants

Downtown Urban Loft above Restaurants
2.0 star property
Perryville
The price is AU$471
includes taxes & fees
28 Dec - 29 Dec
Downtown Urban Loft above Restaurants
Property grounds
New! Luxury Meets Nature - TreeRise at BaseCamp

New! Luxury Meets Nature - TreeRise at BaseCamp

New! Luxury Meets Nature - TreeRise at BaseCamp
2.0 star property
Perryville
10.0 out of 10, Exceptional, (2)
"Our visit was short but so special. Waylon and Kaci have created a sweet haven of rest in the woods of Missouri. We so appreciated the chance to unplug for a bit. Can’t recommend enough! "
United States
Amber S.
New! Luxury Meets Nature - TreeRise at BaseCamp
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Perry County Hotel Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent
"Great stay"
Chris 1-night trip
Posted 1 day ago
Pear Tree Inn Cape Girardeau Near the Medical Center

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