Des Moines County Holiday Rentals

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Our top choices for Des Moines County holiday rentals

10.0 out of 10, Exceptional, (1)
"Nice clean cozy apartment "
United States
John W.
The price is AU$343
includes taxes & fees
1 Jan - 2 Jan 2026
Chic & Luxurious 1BD - Modern Apt. Near Downtown, Quick Walk to Bakery & Pizza!
The price is AU$368
includes taxes & fees
29 Dec - 30 Dec
Luxury Historic 2BD - Modern Comfort Near Downtown, Steps Away from New Bakery
10.0 out of 10, Exceptional, (12)
"Everything as advertised. It was a great place to stay. "
United States
Charles W.
The price is AU$445
includes taxes & fees
29 Dec - 30 Dec
Brand New SPACIOUS 2 BR Downtown Burlington! Unit 302N
9.8 out of 10, Exceptional, (12)
"Very nice place to stay"
United States
Jodi H.
The price is AU$445
includes taxes & fees
10 Jan - 11 Jan 2026
Brand New Spacious 2 BR Downtown Burlington! Unit 301S
3.0 star property
10.0 out of 10, Exceptional, (2)
"Outstanding value and extremely nice place, you won't be disappointed. "
United States
Joe
The price is AU$302
includes taxes & fees
29 Dec - 30 Dec
Idyllic Biggsville Vacation Rental: 10 Mi to River
3.0 star property
9.8 out of 10, Exceptional, (424)
"Very nice comfortable property"
United States
Carie
The price is AU$227
includes taxes & fees
29 Dec - 30 Dec
Nauvoo Vacation Villas & Condos

Holiday Home in Biggsville

Cozy House
10.0 out of 10, Exceptional, (5)
"This was a perfect place for our stay. House was clean and comfortable. Neighbor was super friendly. Couldn’t be happier."
United States
Thomas B.
The price is AU$266
includes taxes & fees
29 Dec - 30 Dec
Cozy House
9.6 out of 10, Exceptional, (84)
"Great place to stay!!"
United States
Lisa G.
The price is AU$232
includes taxes & fees
8 Jan - 9 Jan 2026
Nauvoo Country Cottage - Sleeps 12

Holiday Home in Biggsville

Home Away From Home
10.0 out of 10, Exceptional, (2)
"Our experience all around was good. Communication with host was easy and they worked with us great. House was clean, in a quite neighborhood and definitely better than a hotel."
United States
Thomas A.
The price is AU$305
includes taxes & fees
29 Dec - 30 Dec
Home Away From Home

Apartment in Fort Madison

Stay in this Unique SE Iowa Apt
10.0 out of 10, Exceptional, (14)
"Would definately stay here agan."
United States
Christina
The price is AU$217
includes taxes & fees
29 Dec - 30 Dec
Stay in this Unique SE Iowa Apt
9.8 out of 10, Exceptional, (85)
"Great location, comfortable beds."
United States
Diane P.
The price is AU$245
includes taxes & fees
4 Jan - 5 Jan 2026
The Red Front Suite - Sleeps 15
10.0 out of 10, Exceptional, (10)
"The check-in was pretty easy and the kitchen had everything we needed to make quick meals. "
United States
Tony H.
The price is AU$236
includes taxes & fees
4 Jan - 5 Jan 2026
Nauvoo Windmill Farmhouse 10-12 people
9.4 out of 10, Exceptional, (16)
"Stayed here while our daughter was at a volleyball camp at Western. Great little place. Will definitely pass on to friends whose kids go to Western and will stay again when we are back down."
United States
Jen A.
The price is AU$229
includes taxes & fees
1 Jan - 2 Jan 2026
Golf and Stay house is next to Twin Oaks Golf Course. Lovely 9 hole golf course.
9.6 out of 10, Exceptional, (39)
"Wonderful property, couldn't have asked for better"
United States
Brandon T.
The price is AU$464
includes taxes & fees
5 Jan - 6 Jan 2026
View Nauvoo and the Mighty Mississippi/Sidon

Apartment in Nauvoo

Mulholland Garden Apartment
9.2 out of 10, Wonderful, (37)
"It was very accommodating and great location!"
United States
Tania J.
The price is AU$141
includes taxes & fees
29 Dec - 30 Dec
Mulholland Garden Apartment

Holiday Home in Oquawka

Oquawka Cottage With River View
9.6 out of 10, Exceptional, (8)
"Cute little cottage, very clean. Wonderful beds. Very peaceful visit. Will come again"
United States
sally
The price is AU$303
includes taxes & fees
26 Jan - 27 Jan 2026
Oquawka Cottage With River View
9.8 out of 10, Exceptional, (21)
"The property is cute and very clean right on the river!! Would definitely stay again!!"
United States
Amy M.
The price is AU$434
includes taxes & fees
28 Jan - 29 Jan 2026
Riverside Waterfront on the Mississippi River

Apartment in Nauvoo

Fairy Bowery
8.4 out of 10, Very good, (55)
"Such a quaint little stay! The property has so much character and charm! Great place to stay!"
United States
Camry
The price is AU$141
includes taxes & fees
5 Jan - 6 Jan 2026
Fairy Bowery
2.0 star property
8.8 out of 10, Excellent, (11)
"Close to all attractions."
United States
Reed C.
The price is AU$232
includes taxes & fees
4 Jan - 5 Jan 2026
Historic Nauvoo Apartment, family friendly.
9.6 out of 10, Exceptional, (14)
"We were there just one night, but enjoyed our stay. The beds were very comfortable, and the property was nice and clean. "
United States
Jason B.
The price is AU$370
includes taxes & fees
10 Jan - 11 Jan 2026
Newly Renovated Full Family Apt. - Centrally Located in Nauvoo - some stairs
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Des Moines County Hotel Reviews

Find out more about Des Moines County

Everything you need to know about Des Moines County holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Des Moines County holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Des Moines County holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Des Moines County holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Des Moines County. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Des Moines County holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Des Moines County holiday rentals we have chosen for you start as low as AU$141 per night. Entering your travel dates in the search wizard you might find even better deals.

How to find incredible deals on Des Moines County rentals

At Expedia, we put the best Des Moines County holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Des Moines County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Des Moines County holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Des Moines County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.