
Barrio de Guadalupe Holidays
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Your De Guadalupe Holiday
Your next great escape is calling with a holiday package to De Guadalupe. Excitement, fun and nothing but great times — you're sure to find it in this neighbourhood. Your trip to De Guadalupe wouldn't be complete without a stop at big-name attractions nearby such as San Cristóbal de las Casas Cathedral, Guadalupe Church and Plaza 31 de Marzo. Expedia is here to put your plans into action. Book your perfect De Guadalupe holiday today.
Our guide on where to stay in Barrio de Guadalupe

Zona Centro
Unique features of Zona Centro include the museums and gardens. Make a stop by Plaza 31 de Marzo or Mesoamerican Museum of Jade while you're exploring the area.
Our pick of the best Barrio de Guadalupe Hotel Deals

Hotel Cielo y Selva, San Cristobal de las Casas
"Is a great place to stay"
Reviewed on 28 May 2026

Yox Hotel Boutique
"Muy buena atencion al cliente. La limpieza excelente, sin embargo la manija de la regadera estaba ropa y no habia secadora de cabello en el bano."
Reviewed on 1 June 2026

Jungla Hotel Boutique
"Very cute hotel but not what we were expecting. First thing I noticed was that the showers never really got hot or stayed hot. They get lukewarm at best. Staffing said that it’s because they were “regaderas de paso” meaning they’re only to rinse then you have to be turning on and off the water so ..."
Reviewed on 1 June 2026
Frequently asked questions
Discover the most popular places to visit in Barrio de Guadalupe

Guadalupe Church
Climb the 79 steps to appreciate the staggering views from this hilltop church. The church itself is a pretty example of colonial architecture.

Santo Domingo Handicraft Market
Spend a delightful morning perusing the myriad colorful stalls at the city’s famous outdoor crafts market. Buy some souvenirs to take home.

Mesoamerican Museum of Jade
Understand the importance that jade held in ancient Mesoamerican cultures at this fascinating museum, where you will find replica masks and jewelry.
Activities

San Juan Chamula and Zinacantán Indigenous Communities

FromSan Cristobal:Zinacantán andSanJuanChamula ENGLISH GUIDE















