Top Hotels Near Carolina Pines Regional Medical Center in Hartsville from AU$105

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
19 Dec - 20 Dec
Tomorrow
20 Dec - 21 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Carolina Pines Regional Medical Center hotels

Reception
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
2.5 star property
4.2 km from Carolina Pines Regional Medical Center
8.6 out of 10, Excellent, (678)
"very friendly older property but clean"
United States
Tamiko
The price is AU$142
includes taxes & fees
26 Dec - 27 Dec
Fairfield Inn by Marriott Hartsville
Dining
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
2.5 star property
4.2 km from Carolina Pines Regional Medical Center
9.2 out of 10, Wonderful, (479)
"Staff was very friendly and accommodating!! Rooms were very clean! "
United States
Julia
The price is AU$207
includes taxes & fees
26 Dec - 27 Dec
Hampton Inn & Suites Hartsville
Rooftop terrace
The Mantissa Hotel

The Mantissa Hotel

The Mantissa Hotel
3.0 star property
4.1 km from Carolina Pines Regional Medical Center
9.2 out of 10, Wonderful, (270)
"Very nice spacious rooms friendly staff"
United States
Duane
The price is AU$252
includes taxes & fees
29 Dec - 30 Dec
The Mantissa Hotel
Free daily continental breakfast
The Landmark Inn

The Landmark Inn

The Landmark Inn
2.5 star property
4.3 km from Carolina Pines Regional Medical Center
7.0 out of 10, Good, (314)
"Great staff"
United States
Thomas
The price is AU$127
includes taxes & fees
20 Dec - 21 Dec
The Landmark Inn
Lobby
Quality Inn Hartsville

Quality Inn Hartsville

Quality Inn Hartsville
2.5 star property
3.8 km from Carolina Pines Regional Medical Center
6.0 out of 10, (329)
"Lady at desk was plesant and helpful. Sstart3ed to ask for our money back"
United States
Cynthia
The price is AU$105
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn Hartsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Carolina Pines Regional Medical Center Hotel Reviews

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

10/10 Excellent
"Plenty of space, but it also had a cozy/comfortable feel. Staff was super friendly and there was a good variety of items available for the free breakfast. Everything was clean, the bed was very comfortable.. Just 5-10 minutes from 95, and plenry of food and shopping options nearby."
Laura 1-night trip
Posted 4 days ago
Comfort Inn & Suites Florence Center Area

Hotels near other Carolina Pines Regional Medical Center attractions

Kalmia Gardens

4.0/5 (27 reviews)
Explore the great outdoors at Kalmia Gardens, a lovely green space in Hartsville. You'll find more to see and do in this walkable area.
See properties

Neptune Island Waterpark

3.8/5 (6 reviews)
Enjoy the thrill rides with your children at Neptune Island Waterpark as part of your trip to Hartsville. While in this walkable area, you can enjoy the restaurants.
See properties

Frequently asked questions

What's the area like around Carolina Pines Regional Medical Center?
Carolina Pines Regional Medical Center is located in Hartsville. Travellers like this welcoming area for its restaurants. You'll find 15 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay close to Carolina Pines Regional Medical Center?
Fairfield Inn by Marriott Hartsville is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. It's located 2.6 mi (4.2 km) from Carolina Pines Regional Medical Center. Other good options within a few miles include Quality Inn Hartsville and Hampton Inn & Suites Hartsville.
How many hotels are there near Carolina Pines Regional Medical Center?
Expedia has 15 hotels and other accommodation options a few miles from Carolina Pines Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Carolina Pines Regional Medical Center, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer near Carolina Pines Regional Medical Center.
What can I see and do near Carolina Pines Regional Medical Center?
Learn about local history at Kalmia Gardens and East Home Avenue Historic District. You might spend a leisurely day outdoors at Byerly Park and Segars-McKinnon Heritage Preserve. Attractions like Hartsville Museum and Center Theatre highlight the local culture.