A coastal town with clear turquoise waters, rocky shores, and white buildings.

Spa Hotels & Resorts in Anna from AU$162

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Anna Spa Hotels

Tonight
24 Sept - 25 Sept
Tomorrow
25 Sept - 26 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Anna hotels with a spa

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
AU$162
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
View all properties

Choose what matters most at spa hotels in Anna

Pool
Breakfast included
Spa pool
4 stars
5 stars

Top Anna Hotel Reviews

Best Western Marion Hotel

Best Western Marion Hotel

10/10 Excellent
"Clean, friendly staff and nice breakfast. Would definitely stay again."
Susan 1-night trip
Posted 1 day ago
Best Western Marion Hotel
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Great hotel, had zero issues and staff was lovely"
Kegan 3-night trip
Posted 3 days ago
Drury Inn & Suites Cape Girardeau
Hampton Inn Carbondale

Hampton Inn Carbondale

8/10 Good
"We had a great experience, our friends however were across the hall and had a TERRIBLE mold issue/smell- it was not handled well advised they needed to reach out to Expedia… please explain why a refund can’t be issued to Expedia…. Then Expedia refund to the travelers… hmmmm"
Amy 1-night trip
Posted 4 days ago
Hampton Inn Carbondale

Frequently asked questions

Looking for a spa hotel in Anna?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Enjoy the local architecture and restaurants in Anna—your day trip starts here. Enjoy the historical sites and natural parks during your holiday. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your holiday.
What's there to see and do in Anna?
Enjoy all that Anna has to offer and visit Shawnee National Forest, Anna City Park and King Neptune Memorial. If you have a bit of extra time while you're in the area, you might want to check out Giant City State Park and Blue Sky Vineyards.
What is a Anna spa hotel?
Spa hotels in Anna provide lodging and have a full on-site spa offering services including therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.

Explore a world of travel with Expedia