Cheap Flights from Des Moines (DSM) to San Antonio (SAT)

View AU$223 flight on Wed, 1 Apr 2026Opens in a new window

Flight 1

Popular airlines from Des Moines International Airport (DSM) to San Antonio International Airport (SAT)

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Cheap Flights from Des Moines (DSM) to San Antonio (SAT)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$446 Return, found 5 days ago
AU$446
Return
found 5 days ago
Select American Airlines flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$446 found 5 days ago
Delta
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$446 Return, found 5 days ago
AU$446
Return
found 5 days ago
Select Delta flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$446 found 5 days ago
American Airlines
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$463 Return, found 5 days ago
AU$463
Return
found 5 days ago
Select American Airlines flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$463 found 5 days ago
American Airlines
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$495 Return, found 5 days ago
AU$495
Return
found 5 days ago
Select American Airlines flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$495 found 5 days ago
American Airlines
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$513 Return, found 5 days ago
AU$513
Return
found 5 days ago
Select American Airlines flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$513 found 5 days ago
American Airlines
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$531 Return, found 5 days ago
AU$531
Return
found 5 days ago
Select American Airlines flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$531 found 5 days ago
American Airlines
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$532 Return, found 5 days ago
AU$532
Return
found 5 days ago
Select American Airlines flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$532 found 5 days ago
United
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$545 Return, found 5 days ago
AU$545
Return
found 5 days ago
Select United flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$545 found 5 days ago
American Airlines
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$547 Return, found 5 days ago
AU$547
Return
found 5 days ago
Select American Airlines flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$547 found 5 days ago
Delta
Wed, 1 Apr - Wed, 8 Apr
DSM
Des Moines
SAT
San Antonio
AU$560 Return, found 5 days ago
AU$560
Return
found 5 days ago
Select Delta flight, departing Wed, 1 Apr from Des Moines to San Antonio, returning Wed, 8 Apr, priced at AU$560 found 5 days ago

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Find the cheapest month to fly from Des Moines (DSM) to San Antonio (SAT)

August is typically the cheapest month to fly

From AU$279 - AU$949 per traveller.

Frequently asked questions

How much is a flight from Des Moines Intl. Airport (DSM) to San Antonio Airport?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price listed for a round-trip flight between DSM and SAT was AU$446. Fares this good don't stick around for long, so make sure you book yours ASAP. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Des Moines Intl. Airport (DSM) to San Antonio Intl. Airport (SAT)?
Most flights can be cancelled online, but each airline has different terms and conditions. If you do decide to cancel your flight, check out our Customer Service Portal and follow the instructions.
How do I find cheap flights from Des Moines Intl. Airport to San Antonio Intl. Airport (SAT) that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Des Moines Intl. Airport (DSM) to SAT flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Des Moines Intl. Airport to San Antonio Airport?
With a flight distance of 1 400 kilometres, it's just a short hop from Des Moines Intl. Airport to SAT. It might be a quick one, but it's still worth packing something to keep you busy on board.
Which airlines fly direct from Des Moines Intl. Airport to San Antonio Intl. Airport (SAT)?
You won't find any airlines operating directly between Des Moines Intl. Airport (DSM) and SAT, so be ready to make at least one stop on your journey. A layover, whether short or long, can be a welcome way to break up a trip!
Are Des Moines Intl. Airport to San Antonio Airport flight tickets cheaper when they're purchased at the last minute?
Last-minute planners can occasionally find a bargain, with some super cheap airfares from Des Moines Intl. Airport (DSM) to San Antonio Intl. Airport (SAT) showing up a few weeks before the departure date. If you'd rather plan ahead, Expedia compares and updates all the best flight deals continually — as early as a year in advance in some cases. It depends on the carrier though, as not all airlines advertise prices that far in advance.

Travel information

Origin airport
Des Moines Intl.
Destination airport
San Antonio Intl.
Return price
AU$446
Distance
1395 km

Book with confidence

Your quick guide to flights from Des Moines to San Antonio

Pick up great flights from Des Moines to San Antonio

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Des Moines to San Antonio. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Des Moines to San Antonio that take around hours.

Find cheap flights from Des Moines to San Antonio

From the great flight deals with prices currently ranging from AU$446 to AU$560, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Des Moines to San Antonio around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to San Antonio is normally in April.

Reasons to book your flight from Des Moines to San Antonio with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Des Moines to San Antonio across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to San Antonio right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Des Moines to San Antonio
*Available to Expedia members.