The biggest bookstore presence in the city is Barnes & Noble. Other locations: 33 E. 17th St., at Union Sq., Flatiron District, PHONE: 212/253-0810. 4 Astor Pl., at Lafayette St., East Village, PHONE: 212/420-1322. 600 5th Ave., at W. 48th St., Midtown West, PHONE: 212/765-0592. 1972 Broadway, at W. 66th St., Upper West Side, PHONE: 212/595-6859. 2289 Broadway, at W. 82nd St., Upper West Side, PHONE: 212/362-8835. 240 E. 86th St., between 2nd and 3rd Aves., Upper East Side, PHONE: 212/794-1962.