This midtown ultramodern brasserie has an unmistakable downtown vibe. The design by architects Diller & Scofidio uses molded pear wood, lime-green resin, pastry-bag sculptures, and digital flat-screen technology to create an otherworldly eating environment. As an added bonus, the contemporary brasserie fare -- served from morning to late night -- is excellent. The baguettes are superb and the daily specials speak French without an accent. Don't leave without sampling dessert. Reservations essential. Subway: 6 to 51st St.